NCT03263325 is a clinical trial of Discarded urine sample in Acute Kidney Injury, sponsored by Boston Children's Hospital.

Who is sponsoring NCT03263325?

NCT03263325 is sponsored by Boston Children's Hospital.

What drugs are being tested in NCT03263325?

Interventions in NCT03263325: Discarded urine sample.

What condition does NCT03263325 study?

NCT03263325 studies Acute Kidney Injury.

Is NCT03263325 still recruiting?

NCT03263325 is currently status unknown. Last updated 17 February 2023.

Last reviewed 2023-02-17 · How we verify

NCT03263325

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of UDP-glucose as a Urinary Biomarker for Early Detection of Cardiac Surgery-associated Pediatric Acute Kidney Injury

Status unknown Last updated 17 February 2023

What this trial tests

trial testing Discarded urine sample in Acute Kidney Injury in 250 participants. Status unknown.

Timeline

25 October 2017

Primary endpoint
1 July 2023

1 August 2023

Quick facts

Lead sponsor	Boston Children's Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	250
Start date	25 October 2017
Primary completion	1 July 2023
Estimated completion	1 August 2023
Sites	1 location across United States

Drugs / interventions tested

Discarded urine sample

Conditions studied

Acute Kidney Injury — all drugs for Acute Kidney Injury →

Sponsor

Boston Children's Hospital

Who can join

Under 8, any sex, with Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute kidney injury (AKI) is common in children after cardiac surgery with a reported incidence of 20-40%. Pediatric AKI has been found to be associated with important short and long-term adverse outcomes. A major challenge to management of AKI after cardiac surgery and cardiopulmonary bypass is the lack of early diagnostic markers. Current diagnostic criteria for AKI in children relies exclusively on elevation of serum creatinine concentration and oliguria. Both of these markers lack sensitivity and specificity, and result in delayed detection of kidney injury. This study aims to determine if UDP-glucose can be used as a urinary biomarker to detect subclinical acute kidney injury following pediatric cardiac surgery with cardiopulmonary bypass.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Toward Precision Medicine: Exploring the Landscape of Biomarkers in Acute Kidney Injury.
Nourie N, Ghaleb R, Lefaucheur C, Louis K. · · 2024 · cited 17× · PMID 38254682 · DOI 10.3390/biom14010082

Verify or expand the search:

Other recruiting trials for Acute Kidney Injury

Currently open trials in the same condition.

NCT07273838 — Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome · Phase 2 · recruiting
NCT07262320 — Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America · recruiting
NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07215702 — A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kid · Phase 2 · recruiting
NCT06654193 — Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury · Phase 1, PHASE2 · recruiting

Other Boston Children's Hospital trials

Trials by the same sponsor.

NCT06804382 — Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP · NA · not yet recruiting
NCT05113394 — Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy · Phase 2 · withdrawn
NCT06434220 — Effect of Predictive Model on ED Physician Assessments of Patient Disposition · NA · not yet recruiting
NCT07476430 — Readiness Outcomes Affecting Return to Sport 3.0 · NA · not yet recruiting
NCT06706336 — Radon Asthma Intervention Trial · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03263325 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Boston Children's Hospital
Last refreshed: 17 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03263325.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing