NCT03263000 is a clinical trial in Blepharospasm, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Who is sponsoring NCT03263000?

NCT03263000 is sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

What condition does NCT03263000 study?

NCT03263000 studies Blepharospasm.

Is NCT03263000 still recruiting?

NCT03263000 is currently terminated. Last updated 26 April 2019.

Last reviewed 2019-04-26 · How we verify

NCT03263000

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Photic Blink Reflex in People With Blepharospasm and Increased Blinking

Terminated Last updated 26 April 2019

What this trial tests

trial in Blepharospasm in 17 participants. Terminated before completion.

Timeline

30 October 2017

Primary endpoint
24 April 2019

24 April 2019

Quick facts

Lead sponsor	National Institute of Neurological Disorders and Stroke (NINDS)
Status	Terminated
Study type	OBSERVATIONAL
Enrollment	17
Start date	30 October 2017
Primary completion	24 April 2019
Estimated completion	24 April 2019
Sites	1 location across United States

Conditions studied

Blepharospasm — all drugs for Blepharospasm →

Sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Who can join

18 and older, any sex, with Blepharospasm. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: Some people who have increased blinking may later develop blepharospasm. Blepharospasm is a neurological disorder that causes involuntary closing of the eyes. Researchers want to learn more about how eyes close in response to different stimuli. They want to study this in healthy people, people with increased blinking, and people with blepharospasm. Objective: To learn how light exposure affects people with blepharospasm. Eligibility: People ages 18 and older with blepharospasm or increased blinking, and healthy volunteers Design: Participants will be screened with: Medical history Physical exam Neurological exam Participants will have up to 5 visits. The number of visits will depend on the number of tests they opt to have. They can opt to have up to 4 tests. Visits last 60-90 minutes. They cannot drink alcohol or caffeinated drinks for at least 12 hours before visits. Visits could include the following tests: Evaluation of eyelid movements. This will be video recorded. Electromyography: Small sticky electrodes are placed on the lower eyelid skin. These are attached to wires. Muscle activity is recorded during blink reflex procedures. Electrical stimulation: An electrode is placed close to the eyebrow. It will deliver small electrical shocks. The strength of the shocks will be enough to provoke a blink. Photic stimulation: A lamp is placed in front of the face. It will deliver single or paired flashes. The flashes will be at various intervals and intensities. Participants will wear a patch over one eye during this test. Combination of electrical and photic stimulation ...

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03263000 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Institute of Neurological Disorders and Stroke (NINDS)
Last refreshed: 26 April 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03263000.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing