NCT03261921 is a Phase 1 clinical trial of Dexamethasone in Caudal Block, sponsored by Cairo University.

Who is sponsoring NCT03261921?

NCT03261921 is sponsored by Cairo University.

What drugs are being tested in NCT03261921?

Interventions in NCT03261921: Dexamethasone, Dexmedetomidine, Bupivacaine.

What condition does NCT03261921 study?

NCT03261921 studies Caudal Block.

Is NCT03261921 still recruiting?

NCT03261921 is currently completed. Last updated 25 August 2017.

Last reviewed 2017-08-25 · How we verify

NCT03261921

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Caudal Combination of Dexamethasone and/or Dexmedetomidine to Bupivacaine in Pediatric Hypospadias Surgery

Completed Phase 1 Last updated 25 August 2017

What this trial tests

Phase 1 trial testing Dexamethasone in Caudal Block in 63 participants. Completed in 7 July 2017.

Timeline

5 June 2016

Primary endpoint
22 June 2017

7 July 2017

Quick facts

Lead sponsor	Cairo University
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	triple
Primary purpose	diagnostic
Enrollment	63
Start date	5 June 2016
Primary completion	22 June 2017
Estimated completion	7 July 2017

Drugs / interventions tested

Dexamethasone (dexamethasone) — full drug profile →
Dexmedetomidine (dexmedetomidine) — full drug profile →
Bupivacaine (BUPIVACAINE) — full drug profile →

Conditions studied

Caudal Block — all drugs for Caudal Block →

Sponsor

Cairo University

Who can join

Adults 1 to 6, male only, with Caudal Block. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

One of the most commonly used regional anesthetic techniques in pediatric surgeries is the caudal epidural block. Its main disadvantage remains the short duration of action. Hence, different additives have been used. Dexmedetomidine as an additive to the local anesthetic bupivacaine in caudal epidural analgesia prolongs the duration of postoperative analgesia so is dexamethasone. The investigators aimed to study the effect of combining both additives in the duration of analgesia, decreasing side effects and decreasing anesthetic doses

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Dexamethasone

Trials testing the same drug.

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NCT07175415 — HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological · Phase 1, PHASE2 · not yet recruiting
NCT07513129 — A Phase 1 Study Of Venetoclax, Dexamethasone, Bortezomib, And Daratumumab (VDBD) For Adolescent And Young Adult Patients · Phase 1 · not yet recruiting
NCT07444710 — Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) · Phase 1 · not yet recruiting
NCT07387926 — Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+ · Phase 1, PHASE2 · not yet recruiting

Other Cairo University trials

Trials by the same sponsor.

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NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03261921 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 25 August 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03261921.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing