NCT03253952 is a clinical trial in Trauma, Spinal Cord, sponsored by Ohio State University.

Who is sponsoring NCT03253952?

NCT03253952 is sponsored by Ohio State University.

What condition does NCT03253952 study?

NCT03253952 studies Trauma, Spinal Cord, SPINAL Fracture.

Is NCT03253952 still recruiting?

NCT03253952 is currently active, enrolled. Last updated 11 August 2025.

Last reviewed 2025-08-11 · How we verify

NCT03253952

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Study of Autonomic Dynamic Dysfunction to Predict Infections After Spinal Cord Injury.

Active, enrolled Last updated 11 August 2025

What this trial tests

trial in Trauma, Spinal Cord in 50 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

29 September 2017

Primary endpoint
30 June 2025

31 December 2027

Quick facts

Lead sponsor	Ohio State University
Status	Active, enrolled
Study type	OBSERVATIONAL
Enrollment	50
Start date	29 September 2017
Primary completion	30 June 2025
Estimated completion	31 December 2027
Sites	1 location across United States

Conditions studied

Trauma, Spinal Cord — all drugs for Trauma, Spinal Cord →
SPINAL Fracture — all drugs for SPINAL Fracture →

Sponsor

Ohio State University

Who can join

18 and older, any sex, with Trauma, Spinal Cord or SPINAL Fracture. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study is designed to investigate whether autonomic shifts (dysautonomia, sympatho-vagal instability) that develop after SCI have value in predicting SCI-associated infections (SCI-AI). SCI-AI impair outcomes by (1) reducing the intrinsic neurological recovery potential and (2) increasing mortality. Heart Rate Variability (HRV) data will be tracked in both the time and frequency domains to discriminate between the relative contribution of sympathetic and parasympathetic innervation to changes in HRV. The ability to predict infections will enable novel treatments thereby reducing infection-associated mortality and improving neurological and functional outcomes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Trauma, Spinal Cord

Currently open trials in the same condition.

NCT05244408 — "SCRIBBLE" Spinal Cord Injury Blood Biomarker Longitudinal Evaluation · recruiting

Other Ohio State University trials

Trials by the same sponsor.

NCT06542458 — Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog · not yet recruiting
NCT07217548 — Solving Stigma Through POV Simulation: Enhancing Pharmacist Empathy-based Practices With Sickle Cell Disease Patients · NA · enrolling by invitation
NCT07215221 — Implementation of TBI-RECOVER in Substance Use Treatment · NA · not yet recruiting
NCT07278427 — Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START · recruiting
NCT07490444 — Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03253952 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ohio State University
Last refreshed: 11 August 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03253952.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing