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NCT03250247: C-TRACT

Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)

Active, enrolled NA Last updated 28 January 2026
What this trial tests

NA trial testing Stents in Deep Vein Thrombosis in 225 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
2 July 2018
Primary endpoint
11 November 2025
27 April 2026

Quick facts

Lead sponsorWashington University School of Medicine
PhaseNA
StatusActive, enrolled
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment225
Start date2 July 2018
Primary completion11 November 2025
Estimated completion27 April 2026
Sites29 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

Washington University School of Medicine

Who can join

18 and older, any sex, with Deep Vein Thrombosis or Venous Stasis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine if the use of image-guided, endovascular therapy (EVT) is an effective strategy with which to reduce Post Thrombotic Syndrome (PTS) disease severity and improve quality of life in patients with established disabling iliac-obstructive post thrombotic syndrome (DIO-PTS).

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Chronic Venous Disease of the Lower Extremities: A State-of-the Art Review.
    Attaran RR, Carr JG. · · 2023 · cited 6× · PMID 39132527 · DOI 10.1016/j.jscai.2022.100538
  2. Angioplasty or stenting for deep venous thrombosis.
    Flumignan RL, Nakano LC, Flumignan CD, Baptista-Silva JC. · · 2025 · cited 4× · PMID 39968829 · DOI 10.1002/14651858.cd011468.pub2
  3. A Clinical Trial of Venous Stent Placement for Post-thrombotic Syndrome: Current Status and Pandemic-related Changes.
    Vedantham S, Parpia S, Kahn SR. · · 2022 · cited 3× · PMID 37261191 · DOI 10.15420/ver.2021.19
  4. Mechanical Thrombectomy for Acute and Subacute Blocked Arteries and Veins in the Lower Limbs: A Health Technology Assessment.
    Ontario Health . · · 2023 · cited 3× · PMID 36818453
  5. Endovascular Therapy for Post-Thrombotic Syndrome - A Randomized Trial.
    Vedantham S, Kahn SR, Marston WA, Weinberg I, et al · · 2026 · cited 2× · PMID 41972998 · DOI 10.1056/nejmoa2519001
  6. A mapping review of Pacific Vascular Symposium 6 initiatives.
    Moreno O, Kumar K, Lurie F, Passman MA, et al · · 2024 · PMID 38135216 · DOI 10.1016/j.jvsv.2023.101723

Verify or expand the search:

Other trials of Stents

Trials testing the same drug.

Other recruiting trials for Deep Vein Thrombosis

Currently open trials in the same condition.

Other Washington University School of Medicine trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03250247.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing