Last reviewed · How we verify
NCT03250247: C-TRACT
Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)
NA trial testing Stents in Deep Vein Thrombosis in 225 participants. Participants enrolled and being followed up; not accepting new ones.
11 November 2025
Quick facts
| Lead sponsor | Washington University School of Medicine |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 225 |
| Start date | 2 July 2018 |
| Primary completion | 11 November 2025 |
| Estimated completion | 27 April 2026 |
| Sites | 29 locations across United States |
Drugs / interventions tested
- Stents
Conditions studied
- Deep Vein Thrombosis — all drugs for Deep Vein Thrombosis →
- Venous Stasis — all drugs for Venous Stasis →
- Venous Insufficiency — all drugs for Venous Insufficiency →
- Venous Leg Ulcer — all drugs for Venous Leg Ulcer →
Sponsor
Washington University School of Medicine
Who can join
18 and older, any sex, with Deep Vein Thrombosis or Venous Stasis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine if the use of image-guided, endovascular therapy (EVT) is an effective strategy with which to reduce Post Thrombotic Syndrome (PTS) disease severity and improve quality of life in patients with established disabling iliac-obstructive post thrombotic syndrome (DIO-PTS).
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Chronic Venous Disease of the Lower Extremities: A State-of-the Art Review.
Attaran RR, Carr JG. · · 2023 · cited 6× · PMID 39132527 · DOI 10.1016/j.jscai.2022.100538 -
Angioplasty or stenting for deep venous thrombosis.
Flumignan RL, Nakano LC, Flumignan CD, Baptista-Silva JC. · · 2025 · cited 4× · PMID 39968829 · DOI 10.1002/14651858.cd011468.pub2 -
A Clinical Trial of Venous Stent Placement for Post-thrombotic Syndrome: Current Status and Pandemic-related Changes.
Vedantham S, Parpia S, Kahn SR. · · 2022 · cited 3× · PMID 37261191 · DOI 10.15420/ver.2021.19 -
Mechanical Thrombectomy for Acute and Subacute Blocked Arteries and Veins in the Lower Limbs: A Health Technology Assessment.
Ontario Health . · · 2023 · cited 3× · PMID 36818453 -
Endovascular Therapy for Post-Thrombotic Syndrome - A Randomized Trial.
Vedantham S, Kahn SR, Marston WA, Weinberg I, et al · · 2026 · cited 2× · PMID 41972998 · DOI 10.1056/nejmoa2519001 -
A mapping review of Pacific Vascular Symposium 6 initiatives.
Moreno O, Kumar K, Lurie F, Passman MA, et al · · 2024 · PMID 38135216 · DOI 10.1016/j.jvsv.2023.101723
Verify or expand the search:
- PubMed search for NCT03250247
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Stents
Trials testing the same drug.
- NCT02327312 — Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty · NA · terminated
Other recruiting trials for Deep Vein Thrombosis
Currently open trials in the same condition.
- NCT06886516 — Apixaban in Thrombocytopenia · EARLY_PHASE1 · recruiting
- NCT06842446 — Systematic Machine Learning Algorithm for Rapid Thrombosis Detection · NA · recruiting
- NCT06581965 — inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Tota · Phase 4 · recruiting
- NCT06989255 — A Multi-center Cohort Study for Conventional Ultrasound Image Set Collection to Create a Data Set for Research Purposes. · recruiting
- NCT06727669 — Longitudinal Cohort of Thrombosis and Hemostasis Diseases · recruiting
Other Washington University School of Medicine trials
Trials by the same sponsor.
- NCT05521997 — Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer · Phase 2 · not yet recruiting
- NCT07101666 — Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Phase 2 · not yet recruiting
- NCT07200089 — Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel) · Phase 1 · not yet recruiting
- NCT07313592 — Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients · not yet recruiting
- NCT07419464 — 5-Fluorouracil Response and Optimization STudy (The FROST Trial) · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03250247 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Washington University School of Medicine
- Last refreshed: 28 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03250247.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing