Last reviewed · How we verify
NCT03250065: SETT
The Sensing ET Tube
NA trial testing Application of prototype sensor to a standard endotracheal tube in Diagnostic Equipment in 16 participants. Completed in 30 September 2017.
31 July 2017
Quick facts
| Lead sponsor | City, University of London |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 16 |
| Start date | 3 March 2017 |
| Primary completion | 31 July 2017 |
| Estimated completion | 30 September 2017 |
| Sites | 2 locations across United Kingdom |
Drugs / interventions tested
- Application of prototype sensor to a standard endotracheal tube
Conditions studied
- Diagnostic Equipment — all drugs for Diagnostic Equipment →
- Oximetry — all drugs for Oximetry →
- Pulse Rate — all drugs for Pulse Rate →
Sponsor
City, University of London
Who can join
18 and older, any sex, with Diagnostic Equipment or Oximetry. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This proposal describes the development of a 'Sensing ET Tube'. This device will replace the standard endotracheal (ET) tube used in anaesthesia and in ventilated intensive care patients and provide key vital signs monitoring utilising optoelectronic sensors. Continuous monitoring of patients' arterial oxygen saturation is essential during surgery, however pulse oximeters often misread or fail altogether as a result of peripheral vasoconstriction, hypotension or hypovolaemia. The Sensing ET Tube will allow continuous measurement of oxygen saturation and other parameters, such as pulse rate, from a single internal site, and will reduce the number of surface sensors placed on the skin and the number of electrical connections to the patient. The applicants have already developed similar sensor technology in the oesophagus and other internal locations. A pilot clinical evaluation of the device will be completed in anaesthetised patients undergoing surgery. The project will lead to further development of a multi-sensor tracheal platform for comprehensive anaesthesia and intensive care monitoring.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Novel Photoplethysmography Sensor for Vital Signs Monitoring from the Human Trachea.
May JM, Phillips JP, Fitchat T, Ramaswamy S, et al · · 2019 · cited 7× · PMID 31581652 · DOI 10.3390/bios9040119
Verify or expand the search:
- PubMed search for NCT03250065
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03250065 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by City, University of London
- Last refreshed: 12 February 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03250065.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing