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NCT03249662
Efficacy of Pain Control in Different Bupivacaine Dose in Periarticular Injection in Bilateral Total Knee Arthroplasty
NA trial testing bupivacaine 200 mg in Bilateral Total Knee Arthroplasty in 60 participants. Completed in 14 September 2020.
14 September 2020
Quick facts
| Lead sponsor | Mahidol University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 60 |
| Start date | 27 September 2017 |
| Primary completion | 14 September 2020 |
| Estimated completion | 14 September 2020 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- bupivacaine 200 mg
- bupivacaine 100 mg — full drug profile →
Conditions studied
- Bilateral Total Knee Arthroplasty — all drugs for Bilateral Total Knee Arthroplasty →
Sponsor
Mahidol University
Who can join
18 and older, any sex, with Bilateral Total Knee Arthroplasty. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To study efficacy of postoperative pain control of different concentrations of bupivacaine for periarticular infiltration, part of multimodal analgesia, in bilateral total knee arthroplasty. To study plasma concentration of bupivacaine in patient who received spinal anesthesia and single shot bilateral adductor canal block and periarticular infiltration with bupivacaine for safety level.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy and safety of different bupivacaine concentrations in periarticular infiltration combined with adductor canal block for bilateral total knee arthroplasty: a randomized controlled trial.
Dej-Arkom S, Pangthipampai P, Chandranipapongse W, Chatsirichareonkul S, et al · · 2024 · cited 3× · PMID 38243272 · DOI 10.1186/s43019-024-00211-y
Verify or expand the search:
- PubMed search for NCT03249662
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03249662 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mahidol University
- Last refreshed: 16 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03249662.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing