NCT03248544

Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Brain Tumor Surgery

Completed NA Last updated 31 July 2018

What this trial tests

NA trial testing vitamin D in Brain Neoplasms in 60 participants. Completed in 30 July 2018.

Timeline

6 July 2017

Primary endpoint
30 July 2018

30 July 2018

Quick facts

Lead sponsor	Shahid Beheshti University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	60
Start date	6 July 2017
Primary completion	30 July 2018
Estimated completion	30 July 2018
Sites	2 locations across Iran

Drugs / interventions tested

• vitamin D
• control

Conditions studied

• Brain Neoplasms — all drugs for Brain Neoplasms →

Sponsor

Shahid Beheshti University

Who can join

18 and older, any sex, with Brain Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Vitamin D supplementation not only has beneficial effects on morbidity and mortality in critically ill patients but it may also lead to alleviate of seizure, brain edema, infection, pain and some other perioperative complications, possibly in part through an attenuation of the immune response.In this trial patients with brain tumor under craniotomy will receive a single high dose vitamin D compared to control group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Single high-dose vitamin D3 injection and clinical outcomes in brain tumor resection: A randomized, controlled clinical trial.
   Hajimohammadebrahim-Ketabforoush M, Shahmohammadi M, Keikhaee M, Eslamian G, et al · · 2021 · cited 6× · PMID 33487259 · DOI 10.1016/j.clnesp.2020.11.027