Last reviewed · How we verify
NCT03248180: GDR
Guided Dose Reduction of Antipsychotic in Patients With Psychosis in Remitted States
trial in Psychosis in 160 participants. Status unknown.
31 December 2020
Quick facts
| Lead sponsor | National Taiwan University Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 160 |
| Start date | 24 July 2017 |
| Primary completion | 31 December 2020 |
| Estimated completion | 31 December 2020 |
| Sites | 1 location across Taiwan |
Conditions studied
Sponsor
National Taiwan University Hospital
Who can join
Adults 18 to 50, any sex, with Psychosis or Remission. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A 2-year prospective observational study comparing a group of patients in remitted states of psychosis undergoing guided antipsychotic dose reduction to a similar group of patients under maintenance antipsychotic treatment with the main outcome of interest that if the rates of relapse of psychosis between these two groups will be different.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Guided antipsychotic reduction to reach minimum effective dose (GARMED) in patients with remitted psychosis: a 2-year randomized controlled trial with a naturalistic cohort.
Liu CC, Hsieh MH, Chien YL, Liu CM, et al · · 2023 · cited 20× · PMID 36896797 · DOI 10.1017/s0033291723000429 -
Dose-tapering trajectories in patients with remitted psychosis undergoing guided antipsychotic reduction to reach minimum effective dose.
Liu CC, Hsieh MH, Chien YL, Liu CM, et al · · 2023 · cited 4× · PMID 37578111 · DOI 10.1192/j.eurpsy.2023.2440 -
Verification of successful maintenance by serum drug level during a guided antipsychotic reduction to reach minimum effective dose (GARMED) trial.
Liu CI, Liu CM, Chiu HH, Chuang CC, et al · · 2024 · cited 2× · PMID 39324399 · DOI 10.1017/s0033291724002356 -
Successful antipsychotic dose tapering leading to better cognition in patients with remitted psychosis: Results of Guided Antipsychotic Reduction to Reach Minimum Effective Dose (GARMED) trial.
Liu CI, Liu CM, Hsieh MH, Lin YT, et al · · 2025 · PMID 40862646 · DOI 10.1017/s0033291725101591
Verify or expand the search:
- PubMed search for NCT03248180
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03248180 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
- Last refreshed: 14 August 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03248180.
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