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NCT03248180: GDR

Guided Dose Reduction of Antipsychotic in Patients With Psychosis in Remitted States

Status unknown Last updated 14 August 2017
What this trial tests

trial in Psychosis in 160 participants. Status unknown.

Timeline
24 July 2017
Primary endpoint
31 December 2020
31 December 2020

Quick facts

Lead sponsorNational Taiwan University Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment160
Start date24 July 2017
Primary completion31 December 2020
Estimated completion31 December 2020
Sites1 location across Taiwan

Conditions studied

Sponsor

National Taiwan University Hospital

Who can join

Adults 18 to 50, any sex, with Psychosis or Remission. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A 2-year prospective observational study comparing a group of patients in remitted states of psychosis undergoing guided antipsychotic dose reduction to a similar group of patients under maintenance antipsychotic treatment with the main outcome of interest that if the rates of relapse of psychosis between these two groups will be different.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Guided antipsychotic reduction to reach minimum effective dose (GARMED) in patients with remitted psychosis: a 2-year randomized controlled trial with a naturalistic cohort.
    Liu CC, Hsieh MH, Chien YL, Liu CM, et al · · 2023 · cited 20× · PMID 36896797 · DOI 10.1017/s0033291723000429
  2. Dose-tapering trajectories in patients with remitted psychosis undergoing guided antipsychotic reduction to reach minimum effective dose.
    Liu CC, Hsieh MH, Chien YL, Liu CM, et al · · 2023 · cited 4× · PMID 37578111 · DOI 10.1192/j.eurpsy.2023.2440
  3. Verification of successful maintenance by serum drug level during a guided antipsychotic reduction to reach minimum effective dose (GARMED) trial.
    Liu CI, Liu CM, Chiu HH, Chuang CC, et al · · 2024 · cited 2× · PMID 39324399 · DOI 10.1017/s0033291724002356
  4. Successful antipsychotic dose tapering leading to better cognition in patients with remitted psychosis: Results of Guided Antipsychotic Reduction to Reach Minimum Effective Dose (GARMED) trial.
    Liu CI, Liu CM, Hsieh MH, Lin YT, et al · · 2025 · PMID 40862646 · DOI 10.1017/s0033291725101591

Verify or expand the search:

Other recruiting trials for Psychosis

Currently open trials in the same condition.

Other National Taiwan University Hospital trials

Trials by the same sponsor.

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Data sources for this page

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