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NCT03240315

Personalized Prediction Strategy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Active, enrolled Last updated 12 January 2026
What this trial tests

trial in Pulmonary Disease, Chronic Obstructive in 442 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
1 August 2016
Primary endpoint
30 September 2026
30 December 2026

Quick facts

Lead sponsorGuangzhou Institute of Respiratory Disease
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment442
Start date1 August 2016
Primary completion30 September 2026
Estimated completion30 December 2026
Sites1 location across China

Conditions studied

Sponsor

Guangzhou Institute of Respiratory Disease

Who can join

40 and older, any sex, with Pulmonary Disease, Chronic Obstructive. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a 3-year longitudinal study designed to establish a personalized prediction and prevention system for acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Data will be prospectively collected from patients with chronic obstructive pulmonary disease (COPD) and healthy control participants, including clinical characteristics, pathophysiological parameters, etiological factors, and immunological information. These data will be analyzed using data mining approaches combined with Internet-based technologies.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Association Between Airway Mucus Plugs and Risk of Moderate-to-Severe Exacerbations in Patients With COPD: Results From a Chinese Prospective Cohort Study.
    Li X, Feng S, Yang Y, Liang Z, et al · · 2025 · cited 9× · PMID 40210091 · DOI 10.1016/j.chest.2025.03.026
  2. Acute exacerbation prediction of COPD based on Auto-metric graph neural network with inspiratory and expiratory chest CT images.
    Wang S, Li W, Zeng N, Xu J, et al · · 2024 · cited 6× · PMID 38601695 · DOI 10.1016/j.heliyon.2024.e28724
  3. The relevance of sputum galectin-7 levels to clinical and prognostic factors in patients with chronic obstructive pulmonary disease: a prospective cohort study from China.
    He W, Li X, Huang H, Tang Z, et al · · 2026 · PMID 41761148 · DOI 10.1186/s12890-026-04171-9

Verify or expand the search:

Other recruiting trials for Pulmonary Disease, Chronic Obstructive

Currently open trials in the same condition.

Other Guangzhou Institute of Respiratory Disease trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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