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NCT03240315
Personalized Prediction Strategy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
trial in Pulmonary Disease, Chronic Obstructive in 442 participants. Participants enrolled and being followed up; not accepting new ones.
30 September 2026
Quick facts
| Lead sponsor | Guangzhou Institute of Respiratory Disease |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 442 |
| Start date | 1 August 2016 |
| Primary completion | 30 September 2026 |
| Estimated completion | 30 December 2026 |
| Sites | 1 location across China |
Conditions studied
- Pulmonary Disease, Chronic Obstructive — all drugs for Pulmonary Disease, Chronic Obstructive →
Sponsor
Guangzhou Institute of Respiratory Disease
Who can join
40 and older, any sex, with Pulmonary Disease, Chronic Obstructive. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a 3-year longitudinal study designed to establish a personalized prediction and prevention system for acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Data will be prospectively collected from patients with chronic obstructive pulmonary disease (COPD) and healthy control participants, including clinical characteristics, pathophysiological parameters, etiological factors, and immunological information. These data will be analyzed using data mining approaches combined with Internet-based technologies.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Association Between Airway Mucus Plugs and Risk of Moderate-to-Severe Exacerbations in Patients With COPD: Results From a Chinese Prospective Cohort Study.
Li X, Feng S, Yang Y, Liang Z, et al · · 2025 · cited 9× · PMID 40210091 · DOI 10.1016/j.chest.2025.03.026 -
Acute exacerbation prediction of COPD based on Auto-metric graph neural network with inspiratory and expiratory chest CT images.
Wang S, Li W, Zeng N, Xu J, et al · · 2024 · cited 6× · PMID 38601695 · DOI 10.1016/j.heliyon.2024.e28724 -
The relevance of sputum galectin-7 levels to clinical and prognostic factors in patients with chronic obstructive pulmonary disease: a prospective cohort study from China.
He W, Li X, Huang H, Tang Z, et al · · 2026 · PMID 41761148 · DOI 10.1186/s12890-026-04171-9
Verify or expand the search:
- PubMed search for NCT03240315
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03240315 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Guangzhou Institute of Respiratory Disease
- Last refreshed: 12 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03240315.
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