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NCT03232086: RECAP
Responses to Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Adults
NA trial testing Clean Air in Exposure to Pollution in 20 participants. Completed in 30 July 2020.
20 January 2019
Quick facts
| Lead sponsor | Environmental Protection Agency (EPA) |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 20 |
| Start date | 16 January 2017 |
| Primary completion | 20 January 2019 |
| Estimated completion | 30 July 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Clean Air
- PM2.5
Conditions studied
- Exposure to Pollution — all drugs for Exposure to Pollution →
Sponsor
Environmental Protection Agency (EPA)
Who can join
Adults 18 to 35, any sex, with Exposure to Pollution. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Purpose: To determine whether exposure to levels of fine particles that are close to the current standard will cause cardiovascular changes in healthy individuals.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults.
Wyatt LH, Devlin RB, Rappold AG, Case MW, et al · · 2020 · cited 25× · PMID 33198760 · DOI 10.1186/s12989-020-00389-5
Verify or expand the search:
- PubMed search for NCT03232086
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Clean Air
Trials testing the same drug.
- NCT05794087 — The Role of Macrophage Activation in Lung Injury Following Ozone Exposure · NA · recruiting
- NCT04315740 — Acute Health Effects Due to Ultrafine Particles From Candles and Cooking · NA · completed
Other recruiting trials for Exposure to Pollution
Currently open trials in the same condition.
- NCT03615742 — Diesel Exhaust Induces Glucocorticoid Resistance · Phase 4 · recruiting
Other Environmental Protection Agency (EPA) trials
Trials by the same sponsor.
- NCT05944770 — ASPIRE Health Tulare County · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03232086 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Environmental Protection Agency (EPA)
- Last refreshed: 5 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03232086.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing