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NCT03230435: QOLAN-DK

Health Related Quality of Life for Patients With Anorexia Nervosa in Denmark.

Status unknown Last updated 6 February 2024
What this trial tests

trial testing Treatment settings as usual. in Anorexia Nervosa in 496 participants. Status unknown.

Timeline
1 March 2017
Primary endpoint
1 February 2024
1 January 2025

Quick facts

Lead sponsorRené Klinkby Støving
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment496
Start date1 March 2017
Primary completion1 February 2024
Estimated completion1 January 2025
Sites1 location across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

René Klinkby Støving

Who can join

Adults 13 to 40, any sex, with Anorexia Nervosa or Health-Related Quality Of Life. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Eating disorders (ED) comprise a multitude of symptoms involving a disturbed body image and a preoccupation with food or bodyweight. EDs are often difficult to treat, in part due to the lack of motivation for improvement. Anorexia nervosa (AN) has the highest mortality rate of any psychiatric disease, and less than half of patients will recover from the disease. Studies have found that patients suffering from AN have impaired health-related quality of life (HRQoL) compared to the general population. It has also been suggested that despite improvement in clinical parameters, patients report deterioration in HRQoL, which is in line with a study finding low agreement between patient perceived outcome and clinician assessed characteristics. To evaluate the patients' perception of their disease, it is important to develop reliable and valid assessment tools. Previously generic questionnaires have been used to assess HRQoL in Danish ED patients, as no disease-specific questionnaires have been developed. Translating and validating a disease-specific questionnaire would provide a useful tool in assessing current treatment and in developing new treatment options. This study aimed to develop a Danish version of an internationally disease-specific HRQoL questionnaire. Furthermore, HRQoL is assessed in patients who have gone through shorter or longer treatment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Explanatory Factors for Disease-Specific Health-Related Quality of Life in Women with Anorexia Nervosa.
    Winkler LA, Gudex C, Lichtenstein MB, Røder ME, et al · · 2021 · cited 6× · PMID 33918786 · DOI 10.3390/jcm10081592

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