Who is sponsoring NCT03221218?

NCT03221218 is sponsored by University of British Columbia.

What drugs are being tested in NCT03221218?

Interventions in NCT03221218: Enhanced screening-informed follow up letter.

What condition does NCT03221218 study?

NCT03221218 studies Brain Concussion.

Is NCT03221218 still recruiting?

NCT03221218 is currently completed. Last updated 2 March 2022.

Last reviewed 2022-03-02 · How we verify

NCT03221218

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Enhanced Screening for Early Treatment Targets After MTBI

Completed NA Last updated 2 March 2022

What this trial tests

NA trial testing Enhanced screening-informed follow up letter in Brain Concussion in 150 participants. Completed in 22 June 2021.

Timeline

9 August 2017

Primary endpoint
30 October 2019

22 June 2021

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	health services research
Enrollment	150
Start date	9 August 2017
Primary completion	30 October 2019
Estimated completion	22 June 2021
Sites	1 location across Canada

Drugs / interventions tested

Enhanced screening-informed follow up letter

Conditions studied

Brain Concussion — all drugs for Brain Concussion →

Sponsor

University of British Columbia

Who can join

Adults 18 to 60, any sex, with Brain Concussion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will examine whether enhancing screening-informed follow-up letters will improve (i) family physician compliance with best practice guidelines for managing persistent symptoms following concussion, and (ii) clinical outcomes from concussion.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Advice to Rest for More Than 2 Days After Mild Traumatic Brain Injury Is Associated With Delayed Return to Productivity: A Case-Control Study.
Silverberg ND, Otamendi T. · · 2019 · cited 31× · PMID 31037065 · DOI 10.3389/fneur.2019.00362
Promoting early treatment for mild traumatic brain injury in primary care with a guideline implementation tool: a pilot cluster randomised trial.
Silverberg ND, Panenka WJ, Lizotte PP, Bayley MT, et al · · 2020 · cited 17× · PMID 33082178 · DOI 10.1136/bmjopen-2019-035527

Verify or expand the search:

Other recruiting trials for Brain Concussion

Currently open trials in the same condition.

NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
NCT06616272 — Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain · NA · recruiting
NCT05498038 — Exercise Reset for Concussion in a Military Environment · NA · recruiting
NCT06413173 — Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric) · NA · recruiting
NCT06365944 — Concussion in French Non-professional Handball League : Efficiency of a Concussion Protocol, the White Card Process · recruiting

Other University of British Columbia trials

Trials by the same sponsor.

NCT07340970 — Sensory Stimuli During Cesarean Delivery · not yet recruiting
NCT07481201 — Phenylalanine Requirements in the Menstrual Phases · NA · not yet recruiting
NCT07492095 — Leucine Requirements in School-Age Children · NA · not yet recruiting
NCT07429305 — Combined Tibial Nerve Stimulation and Standing for People With SCI · NA · recruiting
NCT07519928 — Exploring the Feasibility and Benefits of Implementing Pelvic Floor Muscle Training During Inpatient Rehabilitation for · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03221218 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of British Columbia
Last refreshed: 2 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03221218.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing