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NCT03220334

Healing Effects of Autologous Platelet Rich Plasma on Gastric Ulcer Caused by Endoscopic Submucosal Dissection

Completed Phase 3 Last updated 7 November 2017
What this trial tests

Phase 3 trial testing Platelet rich plasma in Platelet-rich Plasma in 20 participants. Completed in 31 October 2017.

Timeline
1 June 2017
Primary endpoint
31 October 2017
31 October 2017

Quick facts

Lead sponsorKeimyung University Dongsan Medical Center
PhasePhase 3
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment20
Start date1 June 2017
Primary completion31 October 2017
Estimated completion31 October 2017
Sites1 location across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Keimyung University Dongsan Medical Center

Who can join

18 and older, any sex, with Platelet-rich Plasma or Endoscopic Submucosal Dissection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In Korea, where the prevalence of gastric tumors is high, the use of ESD as a treatment for gastric cancer will continue to increase. Considering that there are no special measures to prevent side effects (bleeding, perforation, etc.) of this procedure, it is possible to reduce the large medical costs through the discovery of substances that can promote gastric mucosal healing. Mechanism of PRP-based materials in the regeneration of gastric mucosal damage can be used to understand the pathophysiology of ulcers. In the future, it can be suggested as a new treatment for gastrointestinal tract damage such as intractable ulcer, perforation, mucosal fistula, gastrointestinal bleeding caused by esophagus, small intestine and large intestine as well as ulcer treatment by endoscopic procedure.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. UEG Week 2018 Poster Presentations
    · 2018 · cited 2×

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Other trials of Platelet rich plasma

Trials testing the same drug.

Other recruiting trials for Platelet-rich Plasma

Currently open trials in the same condition.

Other Keimyung University Dongsan Medical Center trials

Trials by the same sponsor.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing