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NCT03219788
Remifentanil and Desflurane Inhalational Anesthesia in Bariatric Surgeries
Phase 2 trial testing Normal Saline in Anesthesia Emergence in 120 participants. Status unknown.
1 November 2017
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 20 July 2017 |
| Primary completion | 1 November 2017 |
| Estimated completion | 1 November 2017 |
Drugs / interventions tested
- Normal Saline
- Remifentanil 0.1 ug/kg — full drug profile →
- Remifentanil 0.2 ug/kg — full drug profile →
Conditions studied
- Anesthesia Emergence — all drugs for Anesthesia Emergence →
Sponsor
Assiut University
Who can join
Adults 18 to 80, any sex, with Anesthesia Emergence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The number of obese and overweighted persons doubled since 1980. They are 600 million in 2014 all over the world. Obesity results in anatomical, physiological and pharmacological changes which represent a challenge for every anesthetist. Difficult airway increases by 30% with obesity and so awake extubation are the preferred technique. Coughing can be alleviated by opioid receptors which play a role in the cough reflex. Remifentanil may be useful as an ultra-short acting opioid and its effect swiftly and predictably disappears after cessation. An emergence cough is attenuated by remifentanil administered via continuous infusion (TCI), and the expected effective effect-site concentrations investigated have ranged from 1.5 to 2.5 ng.ml/L.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03219788
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Assiut University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03219788 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 18 July 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03219788.
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