Adults 14 to 18, any sex, with Prescription Drug Abuse or Substance Abuse. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Prescription Drug Misuse (i.e., Prescription Drug Use Without a Doctor's Prescription)Primary· Assessed at pre-test and post-test assessment, post-test assessment approximately 2-4 weeks post-intervention reported
This measure includes prescription drug misuse of sedatives, painkillers, and stimulants.
Frequency of sedative, painkiller, and stimulant use without a doctor's prescription; measured on a 9-point scale, including Never (1), A few times but NOT in the past year (2), A few times a year (3), Once a month (4), A few times a month (5), Once a week (6), A few times a week (7), Once a day (8), More than once a day (9);
Unabbreviated scale title: Prescription Drug Misuse (i.e., prescription drug use without a doctor's prescription); Minimum value = 1; maximum value = 9; Higher scores are a worse o
Prescription sedative misuse
Group
Value
95% CI
LST High School Hybrid
1.06
± 0.02
Treatment as Usual (Control)
1.12
± 0.03
Prescription painkiller misuse
Group
Value
95% CI
LST High School Hybrid
1.11
± 0.03
Treatment as Usual (Control)
1.13
± 0.04
Prescription stimulant misuse
Group
Value
95% CI
LST High School Hybrid
1.09
± 0.02
Treatment as Usual (Control)
1.11
± 0.04
Perceived Risk of Prescription Drug MisuseSecondary· Assessed at pre-test and post-test assessment, post-test assessment approximately 2-4 weeks post-intervention reported
This measure includes perceived risk of harm associated with using prescription sedatives, painkillers, and stimulants when prescribed for someone else, measured on a 4-point scale from "No Risk" to "Great Risk;" also option for "Can't say, drug unfamiliar";
Unabbreviated scale title: Perceived Risk of Prescription Drug Misuse; Minimum value = 1; maximum value = 4; Higher scores are a better outcome
Prescription sedatives, risk o harm
Group
Value
95% CI
LST High School Hybrid
2.71
± 0.02
Treatment as Usual (Control)
2.59
± 0.03
Prescription painkillers, risk o harm
Group
Value
95% CI
LST High School Hybrid
2.75
± 0.02
Treatment as Usual (Control)
2.58
± 0.03
Prescription stimulants, risk o harm
Group
Value
95% CI
LST High School Hybrid
2.71
± 0.02
Treatment as Usual (Control)
2.58
± 0.03
Sponsor's own description
This project will develop and evaluate a program to prevent prescription drug misuse in high school students
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Health Promotion Associates, Inc.
Last refreshed: 10 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03219190.