Last reviewed · How we verify
Spinal Prilocaine for Caesarian Sections
Prilocaine theoretically could provide faster onset because of its lower pKa (7,7) compared to bupivacaine (8,1). The primary objective of this prospective double blind randomized trial is to determine block onset of spinal hyperbaric prilocaine compared to bupivacaine, both with a small dose of sufentanyl as an additive.The primary hypothesis is that a significant larger amount of patients will gain surgical readiness within 8 minutes after spinal injection of prilocaine with sufentanyl compared to bupivacaine with sufentanyl. Surgical readiness is defined as a sensory block level of T5 tested by loss of cold sensation.
Details
| Lead sponsor | University Hospital, Antwerp |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 182 |
| Start date | Tue Aug 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun May 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Combined Spinal Epidural Anesthesia
- Prilocaine
- Bupivacaine
- Pain
Interventions
- combined spinal epidural anaesthesia
- Prilocaine
- Bupivacaine
Countries
Belgium