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NCT03218904

Glycogen Storage Disease Breath Test Study

Completed NA Last updated 27 January 2025
What this trial tests

NA trial testing Glucose intake in Patient Compliance in 14 participants. Completed in 24 January 2025.

Timeline
17 March 2017
Primary endpoint
23 October 2021
24 January 2025

Quick facts

Lead sponsorUniversity of British Columbia
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designsequential
Maskingnone
Primary purposehealth services research
Enrollment14
Start date17 March 2017
Primary completion23 October 2021
Estimated completion24 January 2025
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

University of British Columbia

Who can join

Adults 5 to 35, any sex, with Patient Compliance or Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Glycogen storage disease type I (GSD I) caused by deficiency of glucose-6-phosphatase enzyme leading to build up of a complex sugar called glycogen in liver and low blood glucose level. Nutritional treatment involves supplying carbohydrates and uncooked cornstarch. Glycosade® (modified cornstarch) has shown promise in maintaining normal blood glucose level in GSD I. But the difficulty in nutritional treatment is determining the best type of carbohydrate to be given to avoid low blood glucose. Thus, there is a need to develop a simple test to examine glucose digestion and measure the utilization of different carbohydrates in GSD I and healthy controls.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Development of minimally invasive <sup>13</sup>C-glucose breath test to examine different exogenous carbohydrate sources in patients with glycogen storage disease type Ia.
    Turki A, Stockler S, Sirrs S, Salvarinova R, et al · · 2022 · cited 1× · PMID 35585965 · DOI 10.1016/j.ymgmr.2022.100880

Verify or expand the search:

Other trials of Glucose intake

Trials testing the same drug.

Other recruiting trials for Patient Compliance

Currently open trials in the same condition.

Other University of British Columbia trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03218904.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing