Last reviewed · How we verify
NCT03218904
Glycogen Storage Disease Breath Test Study
NA trial testing Glucose intake in Patient Compliance in 14 participants. Completed in 24 January 2025.
23 October 2021
Quick facts
| Lead sponsor | University of British Columbia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | sequential |
| Masking | none |
| Primary purpose | health services research |
| Enrollment | 14 |
| Start date | 17 March 2017 |
| Primary completion | 23 October 2021 |
| Estimated completion | 24 January 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Glucose intake
- Carbohydrates intake
Conditions studied
- Patient Compliance — all drugs for Patient Compliance →
- Healthy — all drugs for Healthy →
Sponsor
University of British Columbia
Who can join
Adults 5 to 35, any sex, with Patient Compliance or Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Glycogen storage disease type I (GSD I) caused by deficiency of glucose-6-phosphatase enzyme leading to build up of a complex sugar called glycogen in liver and low blood glucose level. Nutritional treatment involves supplying carbohydrates and uncooked cornstarch. Glycosade® (modified cornstarch) has shown promise in maintaining normal blood glucose level in GSD I. But the difficulty in nutritional treatment is determining the best type of carbohydrate to be given to avoid low blood glucose. Thus, there is a need to develop a simple test to examine glucose digestion and measure the utilization of different carbohydrates in GSD I and healthy controls.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Development of minimally invasive <sup>13</sup>C-glucose breath test to examine different exogenous carbohydrate sources in patients with glycogen storage disease type Ia.
Turki A, Stockler S, Sirrs S, Salvarinova R, et al · · 2022 · cited 1× · PMID 35585965 · DOI 10.1016/j.ymgmr.2022.100880
Verify or expand the search:
- PubMed search for NCT03218904
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03218904 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of British Columbia
- Last refreshed: 27 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03218904.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing