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NCT03217305
Neurally Adjusted Ventilatory Assist (NAVA) vs Pressure Support Ventilation After Cardiac Surgery
NA trial testing NAVA in Ventilator Lung in 20 participants. Participants enrolled and being followed up; not accepting new ones.
30 September 2025
Quick facts
| Lead sponsor | Sahlgrenska University Hospital |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 30 August 2016 |
| Primary completion | 30 September 2025 |
| Estimated completion | 30 November 2025 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- NAVA
Conditions studied
- Ventilator Lung — all drugs for Ventilator Lung →
Sponsor
Sahlgrenska University Hospital
Who can join
Adults 18 to 84, any sex, with Ventilator Lung. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study compares two different ventilation modes, Pressure support ventilation vs. Neuronally Adjusted Ventilatory Assist, in postcardiac surgery patients. Of special interest is shunt and alveolar deadspace and ventral vs. dorsal ventilation.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Neurally adjusted ventilatory assist vs pressure support ventilation: short-term effects on shunt and dead space after cardiac surgery.
Martinsson A, Lundholm C, Ricksten SE, Oras J, et al · · 2025 · PMID 41423634 · DOI 10.1038/s41598-025-33097-1 -
Neurally Adjusted Ventilatory Assist vs Pressure Support Ventilation: Short-Term Effects on Shunt and Dead Space after Cardiac Surgery
Martinsson A, Lundholm C, Ricksten S, Oras J, et al · · 2025 · DOI 10.21203/rs.3.rs-7502329/v1
Verify or expand the search:
- PubMed search for NCT03217305
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of NAVA
Trials testing the same drug.
- NCT05219643 — Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation · NA · completed
- NCT04821453 — NAVA vs. CMV Crossover in Severe BPD · NA · terminated
- NCT03395795 — Trial Evaluating the Interest of Noninvasive Ventilation in NAVA Mode in Respiratory Decompensations Children With Infan · NA · completed
- NCT03242057 — Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA · NA · completed
- NCT03018483 — Mechanical Ventilation- Weaning and Thoracic Impedance Tomography · NA · unknown
Other recruiting trials for Ventilator Lung
Currently open trials in the same condition.
- NCT06542107 — Weaning From Mechanical Ventilation in Patients With Acute Brain Injury · recruiting
- NCT05726578 — Integrated Echocardiography and Chest Ultrasound Assessment of Lung Recruitment in Preterm Infants · NA · recruiting
- NCT05875883 — Phrenic Identification in the ICU · active not recruiting
- NCT06361420 — Driving Pressure-guided Lung Protective Ventilation · NA · recruiting
- NCT06483529 — Respiratory Mechanics Measurement of Ventilated Patients Through Low-frequency Oscillometry Technique · NA · recruiting
Other Sahlgrenska University Hospital trials
Trials by the same sponsor.
- NCT07491094 — Repeated Examinations for Typing Pulmonary Embolism · recruiting
- NCT07524608 — Implementing an Evidence-based, Standardized Care Bundle Targeting Register Nurses and Anaesthesiologists, to Enhance Pa · not yet recruiting
- NCT07498959 — Primary RPLND Versus Systemic Chemotherapy in Good-prognosis Metastatic Testicular Cancer · NA · recruiting
- NCT06896578 — Latitude - Lateral Lymph Node Attitude Study · NA · not yet recruiting
- NCT07035600 — Walking and Sitting Difficulties After Rectal Cancer Surgery · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03217305 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sahlgrenska University Hospital
- Last refreshed: 15 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03217305.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing