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NCT03216577: hOPeFUL
Outcomes of Purpura FULminans in Adults - The hOPeFUL Study
trial testing Phone interview measuring health-related quality of life variables in Purpura Fulminans in 74 participants. Completed in 8 March 2018.
8 March 2018
Quick facts
| Lead sponsor | Henri Mondor University Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 74 |
| Start date | 27 July 2017 |
| Primary completion | 8 March 2018 |
| Estimated completion | 8 March 2018 |
| Sites | 26 locations across France |
Drugs / interventions tested
- Phone interview measuring health-related quality of life variables
Conditions studied
- Purpura Fulminans — all drugs for Purpura Fulminans →
Sponsor
Henri Mondor University Hospital
Who can join
18 and older, any sex, with Purpura Fulminans. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Purpura fulminans (PF) is a rare life-threatening infectious disease characterized by the association of a sudden and extensive purpura together with acute circulatory failure. The mortality of PF has been reported to be as high as 50% in previous adult series. Additionally, patients surviving to the early phase of PF are exposed to a high risk of limb amputation. The hOPeFUL study aims at assessing the short and long term outcomes of adult patients admitted in the intensive care unit for a purpura fulminans.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical spectrum and short-term outcome of adult patients with purpura fulminans: a French multicenter retrospective cohort study.
Contou D, Sonneville R, Canoui-Poitrine F, Colin G, et al · · 2018 · cited 37× · PMID 30128591 · DOI 10.1007/s00134-018-5341-3 -
Long-term Quality of Life in Adult Patients Surviving Purpura Fulminans: An Exposed-Unexposed Multicenter Cohort Study.
Contou D, Canoui-Poitrine F, Coudroy R, Préau S, et al · · 2019 · cited 12× · PMID 30335142 · DOI 10.1093/cid/ciy901
Verify or expand the search:
- PubMed search for NCT03216577
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03216577 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Henri Mondor University Hospital
- Last refreshed: 9 March 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03216577.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing