NCT03213886: VITAMINA_D

The Effect of Supplementation of Vitamin D Deficiency in Older People With Acute Hip Fracture:

Completed Phase 4 Last updated 2 February 2021

What this trial tests

Phase 4 trial testing Calcifediol (Vitamin D) in Hip Fracture in 50 participants. Completed in 30 July 2020.

Timeline

1 January 2018

Primary endpoint
20 April 2019

30 July 2020

Quick facts

Lead sponsor	Leonor Cuadra Llopart
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	50
Start date	1 January 2018
Primary completion	20 April 2019
Estimated completion	30 July 2020
Sites	1 location across Spain

Drugs / interventions tested

• Calcifediol (Vitamin D) — full drug profile →

Conditions studied

• Hip Fracture — all drugs for Hip Fracture →
• Vitamin D Deficiency — all drugs for Vitamin D Deficiency →

Sponsor

Leonor Cuadra Llopart

Who can join

75 and older, any sex, with Hip Fracture or Vitamin D Deficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will be done to evaluate the effect of load dose of vitamin D compared to the dose of usual clinical practice, in improving mobility and reducing disability in older people following a hip fracture.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Efficacy of two calcifediol supplementation regimens in older adults post-hip fracture surgery. A clinical trial.
   Cuadra-Llopart L, Salvà Casanovas A, Cerdà Mas G, Jovell-Fernández E. · · 2026 · PMID 40952661 · DOI 10.1007/s41999-025-01303-y