NCT03213561

Stable and Independent Communication Brain-computer Interfaces

Terminated NA Last updated 30 March 2020

What this trial tests

NA trial testing Stable and Independent Brain-computer Interfaces for Communication in Healthy in 10 participants. Terminated before completion.

Timeline

11 July 2017

Primary endpoint
22 November 2019

22 November 2019

Quick facts

Lead sponsor	Tomislav Milekovic
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Design	sequential
Masking	none
Primary purpose	supportive care
Enrollment	10
Start date	11 July 2017
Primary completion	22 November 2019
Estimated completion	22 November 2019
Sites	1 location across Switzerland

Drugs / interventions tested

• Stable and Independent Brain-computer Interfaces for Communication

Conditions studied

• Healthy — all drugs for Healthy →
• Tetraplegia — all drugs for Tetraplegia →
• Locked-in Syndrome — all drugs for Locked-in Syndrome →

Sponsor

Tomislav Milekovic

Who can join

18 and older, any sex, with Healthy or Tetraplegia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

People with locked-in syndrome cannot move their limbs or talk because of a motor impairment, but remain conscious and intellectually awake. Restoring the ability to communicate to people with locked-in syndrome will have a positive effect on their quality of life, will enable them to reintegrate into society and increase their capacity to lead productive and fulfilling lives. This study sims to develop a new assisted communication device based on a brain-computer interface, a system that allows the user to control a computer with his brain activity. The investigators will develop this brain-computer system for long-term stability and independent use by using adaptive decoders. The investigators will test the long-term stability and independence of this system with healthy volunteers, people with tetraplegia and people with locked-in syndrome over time periods of several months.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation.
   Young MJ, Lin DJ, Hochberg LR. · · 2021 · cited 35× · PMID 33742433 · DOI 10.1055/s-0041-1725137