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NCT03210220

Efficacy of Preoperative Pectoral Nerve Block for Intraoperative Opioid Sparing Effect and Postoperative Analgesia

Completed NA Results posted Last updated 18 November 2019
What this trial tests

NA trial testing Pecs II block in Breast Cancer in 40 participants. Completed in 1 August 2019.

Timeline
29 August 2017
Primary endpoint
30 December 2018
1 August 2019

Quick facts

Lead sponsorGachon University Gil Medical Center
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposehealth services research
Enrollment40
Start date29 August 2017
Primary completion30 December 2018
Estimated completion1 August 2019
Sites1 location across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Gachon University Gil Medical Center

Who can join

Adults 20 to 65, female only, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Intraoperative Remifentanil Consumption Primary · whole intraoperative period

Intraoperative remifentanil consumption during surgery(whole intraoperative period)

GroupValue95% CI
Pecs Group6.75± 2.18
Control Group10.12± 3.68

Sponsor's own description

The purpose of this study is to determine whether pectoral nerves blocks(PECS) would reduces the opioid consumption during the surgery and postoperative pain after breast cancer surgery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Pectoral Nerve (PECs) block for postoperative analgesia-a systematic review and meta-analysis with trial sequential analysis.
    Jin Z, Li R, Gan TJ, He Y, et al · · 2020 · cited 17× · PMID 32211121
  2. Remifentanil-Sparing Effect of Pectoral Nerve Block Type II in Breast Surgery under Surgical Pleth Index-Guided Analgesia during Total Intravenous Anesthesia.
    Choi JJ, Jo YY, Kim SH, Jung WS, et al · · 2019 · cited 17× · PMID 31394854 · DOI 10.3390/jcm8081181

Verify or expand the search:

Other recruiting trials for Breast Cancer

Currently open trials in the same condition.

Other Gachon University Gil Medical Center trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03210220.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing