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NCT03209843: PERFECTO
Post-stenting Assessment of Reendothelialization With OFDI After CTO Procedure (PERFECTO)
NA trial testing Percutaneous recanalization of chronic total occlusion in Chronic Total Occlusion of Coronary Artery in 122 participants. Completed in 12 February 2021.
12 February 2021
Quick facts
| Lead sponsor | Poitiers University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 122 |
| Start date | 7 March 2018 |
| Primary completion | 12 February 2021 |
| Estimated completion | 12 February 2021 |
| Sites | 7 locations across France |
Drugs / interventions tested
- Percutaneous recanalization of chronic total occlusion
Conditions studied
- Chronic Total Occlusion of Coronary Artery — all drugs for Chronic Total Occlusion of Coronary Artery →
- Optical Coherence Tomography — all drugs for Optical Coherence Tomography →
- Ischemic Cardiomyopathy — all drugs for Ischemic Cardiomyopathy →
- Neointimal Hyperplasia — all drugs for Neointimal Hyperplasia →
Sponsor
Poitiers University Hospital
Who can join
18 and older, any sex, with Chronic Total Occlusion of Coronary Artery or Optical Coherence Tomography. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of PERFECTO is to assess the reendothelialization at 3 months after successfully CTO percutaneous intervention (PCI) with new generation drug eluting stent (DES) by OFDI analysis. Designed as a multicentric, observational and prospective study which will be conducted at University Hospital of Poitiers (France), a systematic OFDI analysis will be realized immediately after CTO-PCI and at 3 months. Known as major predictive factors of stent thrombosis, percentages of malapposition, uncovered struts and neointimal hyperplasia proliferation will be measured over the entire length of each stent implanted combining in a composite primary endpoint.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Optical Coherence Tomography to Better Assess Chronic Total Occlusion Percutaneous Intervention Results: The PERFECTO Study.
Levesque S, Faurie B, Lattuca B, Lemoine J, et al · · 2025 · PMID 40930013 · DOI 10.1016/j.jacadv.2025.102125
Verify or expand the search:
- PubMed search for NCT03209843
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Total Occlusion of Coronary Artery
Currently open trials in the same condition.
- NCT06414551 — Calcification on CTCA of a CTO and PCI Outcomes · recruiting
- NCT06193954 — VasoStar Vibrational Guidewire System to Facilitate Crossing Coronary Artery Chronic Total Occlusions · NA · recruiting
- NCT03756870 — Revascularization Versus Optimal Medical Therapy of Chronic Total Coronary Occlusions on Left Ventricular Ischemia Reduc · NA · recruiting
- NCT03563417 — ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO · NA · recruiting
- NCT03392415 — The NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion · NA · active not recruiting
Other Poitiers University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03209843 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Poitiers University Hospital
- Last refreshed: 14 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03209843.
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