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NCT03208699: EXPALI

EXPert System, ALImentary

Completed Last updated 6 July 2017
What this trial tests

trial in Eating Disorder Symptom in 256 participants. Completed in 31 December 2015.

Timeline
1 October 2015
Primary endpoint
1 October 2015
31 December 2015

Quick facts

Lead sponsorMarie-Pierre TAVOLACCI
StatusCompleted
Study typeOBSERVATIONAL
Enrollment256
Start date1 October 2015
Primary completion1 October 2015
Estimated completion31 December 2015

Conditions studied

Sponsor

Marie-Pierre TAVOLACCI

Who can join

18 and older, any sex, with Eating Disorder Symptom. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Eating disorders (ED) are often undetected in the general population resulting in delayed treatment. The SCOFF questionnaire has been validated for eating disorders screening in primary care, but does not identify the type of eating disorder. Objective: Investigators evaluated the performance of a clinical algorithm (ExpaliTM) combining answers to SCOFF questionnaire with Body Mass Index (BMI) to identify four Broad Categories of ED derived from DSM-5. Design: Clinical algorithm (ExpaliTM) was developped from 104 combinations of BMI levels and answers to five SCOFF questions. Two senior ED specialists allocated each combination to one of the four Broad Categories of ED (DSM-5 diagnostics): restrictive disorder (anorexia nervosa typical, atypical and restrictive food intake disorders), bulimic disorder (typical and with low frequency or duration), hyperphagic disorder (binge eating disorders typical and with low frequency or duration) and other specified ED. The performance of ExpaliTM was evaluated on data from patients referred to the Nutrition Department including a precise DSM-5 diagnosis of ED, a positive SCOFF test (at least 2 "yes" answers) and BMI. Sensitivity, specificity values with a 95% confidence interval (95% CI) and Youden index were calculated for each category.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing