NCT03208478

Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions

Completed NA Last updated 24 July 2023

What this trial tests

NA trial testing Adductor Canal perineural catheter placement in Pain, Postoperative in 60 participants. Completed in 30 April 2023.

Timeline

18 June 2018

Primary endpoint
30 April 2023

30 April 2023

Quick facts

Lead sponsor	Stanford University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	60
Start date	18 June 2018
Primary completion	30 April 2023
Estimated completion	30 April 2023
Sites	1 location across United States

Drugs / interventions tested

• Adductor Canal perineural catheter placement
• Femoral Nerve perineural catheter placement
• Nimbus pump (Infutronix)

Conditions studied

• Pain, Postoperative — all drugs for Pain, Postoperative →
• Anterior Cruciate Ligament Injury — all drugs for Anterior Cruciate Ligament Injury →

Sponsor

Stanford University

Who can join

18 and older, any sex, with Pain, Postoperative or Anterior Cruciate Ligament Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Nerve blocks are used to provide pain control after moderately painful orthopedic surgeries. Anterior Cruciate Ligament (ACL) reconstruction with patellar autograft is a painful orthopedic procedure performed after traumatic injury to the knee. Many patients undergoing ACL reconstruction receive a nerve block as part of their anesthetic care. These blocks can be performed in different locations along the femoral nerve, with advantages and disadvantages to each location. Recently published evidence indicates that there is no short-term difference in pain control between the two commonly-targeted locations ("Adductor Canal" and "Femoral"). However, studies involving patients undergoing total knee arthroplasty indicate that femoral blocks provide better pain control with movement than adductor canal blocks. As many patients undergoing ACL reconstruction use continuous passive motion (CPM) machines as part of rehabilitation starting on post-operative day one, the investigators hypothesize that pain control and quality of recovery in the first 48 hours after surgery will be superior with a continuous femoral block than with a continuous adductor canal block. The investigators plan to study this by randomizing patients presenting for ACL reconstruction to receive either a continuous femoral or continuous adductor canal block (both considered adequate means of pain control), and following them to 48 hours to determine the level of pain, quality of recovery score, opioid use, and CPM compliance.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Adductor canal blocks for postoperative pain treatment in adults undergoing knee surgery.
   Schnabel A, Reichl SU, Weibel S, Zahn PK, et al · · 2019 · cited 16× · PMID 31684698 · DOI 10.1002/14651858.cd012262.pub2