NCT03205254

Effects of Short-term Diet on HDL Composition and Function

Completed NA Last updated 12 August 2021

What this trial tests

NA trial testing Mediterranean Diet in Diet Modification in 10 participants. Completed in 1 July 2019.

Timeline

28 March 2016

Primary endpoint
1 July 2019

1 July 2019

Quick facts

Lead sponsor	University of California, Davis
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	basic science
Enrollment	10
Start date	28 March 2016
Primary completion	1 July 2019
Estimated completion	1 July 2019
Sites	1 location across United States

Drugs / interventions tested

• Mediterranean Diet
• Fast food diet

Conditions studied

• Diet Modification — all drugs for Diet Modification →
• HDL — all drugs for HDL →
• Inflammation — all drugs for Inflammation →

Sponsor

University of California, Davis

Who can join

Adults 19 to 30, any sex, with Diet Modification or HDL. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of this study is to generate preliminary data on the effects of a short-term diet of either fast food or Mediterranean type diet on HDL and microbiota composition and function in healthy subjects, which includes both normal weight and overweight/obese subjects.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Site-Specific Glycoprofiles of HDL-Associated ApoE are Correlated with HDL Functional Capacity and Unaffected by Short-Term Diet.
   Zhu C, Wong M, Li Q, Sawrey-Kubicek L, et al · · 2019 · cited 27× · PMID 31545048 · DOI 10.1021/acs.jproteome.9b00450