Who is sponsoring NCT03201991?

NCT03201991 is sponsored by University of Kansas Medical Center.

What drugs are being tested in NCT03201991?

Interventions in NCT03201991: Resistance Exercise Program.

What condition does NCT03201991 study?

NCT03201991 studies Amyotrophic Lateral Sclerosis.

Is NCT03201991 still recruiting?

NCT03201991 is currently completed. Last updated 19 December 2019.

Last reviewed 2019-12-19 · How we verify

NCT03201991: ADVANCE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ALS Study Determining Various Biomarkers and Strength Comparison After Exercise

Completed NA Last updated 19 December 2019

What this trial tests

NA trial testing Resistance Exercise Program in Amyotrophic Lateral Sclerosis in 9 participants. Completed in 18 April 2018.

Timeline

1 May 2017

Primary endpoint
18 April 2018

18 April 2018

Quick facts

Lead sponsor	University of Kansas Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	prevention
Enrollment	9
Start date	1 May 2017
Primary completion	18 April 2018
Estimated completion	18 April 2018
Sites	1 location across United States

Drugs / interventions tested

Resistance Exercise Program

Conditions studied

Amyotrophic Lateral Sclerosis — all drugs for Amyotrophic Lateral Sclerosis →

Sponsor

University of Kansas Medical Center

Who can join

18 and older, any sex, with Amyotrophic Lateral Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine the muscle strength of a muscle in the thigh after 12 weeks of home exercise.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Immunosenescence in aging and neurodegenerative diseases: evidence, key hallmarks, and therapeutic implications.
Chen Z, Mao Z, Tang W, Shi Y, et al · · 2025 · cited 4× · PMID 41299782 · DOI 10.1186/s40035-025-00517-1
Resistance exercise in early-stage ALS patients, ALSFRS-R, Sickness Impact Profile ALS-19, and muscle transcriptome: a pilot study.
Jawdat O, Rucker J, Nakano T, Takeno K, et al · · 2024 · cited 4× · PMID 39289471 · DOI 10.1038/s41598-024-72355-6

Verify or expand the search:

Other trials of Resistance Exercise Program

Trials testing the same drug.

NCT07400419 — Effects of Resistance Exercise Among TGD Individuals Initiating Estrogen-Based Gender-Affirming Hormone Therapy · NA · recruiting
NCT07303543 — Preventing Muscle Loss After Bariatric Surgery: Protein-Collagen Supplementation and Resistance Exercise · NA · recruiting

Other recruiting trials for Amyotrophic Lateral Sclerosis

Currently open trials in the same condition.

NCT07502677 — Diagnostic Accuracy of SleepImage Technology for Detecting Respiratory Failure in Patients With Amyotrophic Lateral Scle · recruiting
NCT07478172 — Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease · NA · recruiting
NCT07204977 — Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS) · Phase 1 · active not recruiting
NCT07290062 — A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants · Phase 1 · recruiting
NCT07259980 — A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Participants With Superoxide Dismutase 1 (SOD- · recruiting

Other University of Kansas Medical Center trials

Trials by the same sponsor.

NCT06636214 — Adapting Changing Talk: Online (CHATO) to CHATO-Inclusive · NA · not yet recruiting
NCT07528963 — KanSurvive 2.0: Testing Enhanced Models of Cancer Survivorship Care for Rural Cancer Survivors in Primary Care Practice · NA · enrolling by invitation
NCT07463755 — Low-Fidelity Driving Simulator Training in Parkinson's Disease. · NA · not yet recruiting
NCT07420621 — Preliminary Effectiveness of Enhanced Text Message + Incentives · NA · recruiting
NCT07491510 — Improving Prenatal Care to Reduce Early Onset Preeclampsia in Low-Income · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03201991 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Kansas Medical Center
Last refreshed: 19 December 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03201991.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing