NCT03201822 is a NA clinical trial of 100 mg of Cocoa Flavanols/70 kg BW in Healthy, sponsored by University of California, Davis.

Who is sponsoring NCT03201822?

NCT03201822 is sponsored by University of California, Davis.

What drugs are being tested in NCT03201822?

Interventions in NCT03201822: 100 mg of Cocoa Flavanols/70 kg BW, 200 mg of Cocoa Flavanols/70 kg BW, 400 mg of Cocoa Flavanols/70 kg BW, 1000 mg of Cocoa Flavanols/70 kg BW.

Is NCT03201822 still recruiting?

NCT03201822 is currently completed. Last updated 28 June 2017.

Last reviewed 2017-06-28 · How we verify

NCT03201822

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intake-dependent Effect of Cocoa Flavanol Absorption, Metabolism and Excretion in Humans

Completed NA Last updated 28 June 2017

What this trial tests

NA trial testing 100 mg of Cocoa Flavanols/70 kg BW in Healthy in 14 participants. Completed in 25 May 2013.

Timeline

1 April 2013

Primary endpoint
25 May 2013

25 May 2013

Quick facts

Lead sponsor	University of California, Davis
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	basic science
Enrollment	14
Start date	1 April 2013
Primary completion	25 May 2013
Estimated completion	25 May 2013
Sites	1 location across United States

Drugs / interventions tested

100 mg of Cocoa Flavanols/70 kg BW
200 mg of Cocoa Flavanols/70 kg BW
400 mg of Cocoa Flavanols/70 kg BW
1000 mg of Cocoa Flavanols/70 kg BW

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

University of California, Davis

Who can join

Adults 25 to 40, male only, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A randomized, double-masked and cross-over dietary intervention study in healthy young adult males to evaluate the concentration of F-derived metabolites in plasma and urine after single acute intakes of F-containing drinks on four different test days.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies.
Ottaviani JI, Fong R, Kimball J, Ensunsa JL, et al · · 2018 · cited 52× · PMID 29959422 · DOI 10.1038/s41598-018-28333-w
Evaluation of (-)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake.
Ottaviani JI, Fong R, Kimball J, Ensunsa JL, et al · · 2019 · cited 24× · PMID 31511603 · DOI 10.1038/s41598-019-49702-z

Verify or expand the search:

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Other University of California, Davis trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03201822 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of California, Davis
Last refreshed: 28 June 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03201822.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing