NCT03198897 (BioHoFH) is a clinical trial in Lipoprotein Lipase Deficiency, sponsored by CENTOGENE GmbH Rostock.

Who is sponsoring NCT03198897?

NCT03198897 is sponsored by CENTOGENE GmbH Rostock.

What condition does NCT03198897 study?

NCT03198897 studies Lipoprotein Lipase Deficiency, Inborn Error of Lipid Metabolism, Corneal Arcus.

Is NCT03198897 still recruiting?

NCT03198897 is currently withdrawn. Last updated 13 February 2023.

Last reviewed 2023-02-13 · How we verify

NCT03198897: BioHoFH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Withdrawn Last updated 13 February 2023

What this trial tests

trial in Lipoprotein Lipase Deficiency. Withdrawn.

Timeline

20 August 2018

Primary endpoint
28 February 2021

28 February 2021

Quick facts

Lead sponsor	CENTOGENE GmbH Rostock
Status	Withdrawn
Study type	OBSERVATIONAL
Start date	20 August 2018
Primary completion	28 February 2021
Estimated completion	28 February 2021
Sites	4 locations across Sri Lanka, Germany, India

Conditions studied

Lipoprotein Lipase Deficiency — all drugs for Lipoprotein Lipase Deficiency →
Inborn Error of Lipid Metabolism — all drugs for Inborn Error of Lipid Metabolism →
Corneal Arcus — all drugs for Corneal Arcus →

Sponsor

CENTOGENE GmbH Rostock

Who can join

2 Months and older, any sex, with Lipoprotein Lipase Deficiency or Inborn Error of Lipid Metabolism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Development of a new MS-based biomarker for the early and sensitive diagnosis of Homozygous familial Hypercholesterolemia from blood

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Genetic Testing for Familial Hypercholesterolemia: Health Technology Assessment.
Ontario Health (Quality) . · · 2022 · cited 6× · PMID 36158868

Verify or expand the search:

Other recruiting trials for Lipoprotein Lipase Deficiency

Currently open trials in the same condition.

NCT04227678 — Postprandial Fatty Acid Metabolism in Subjects With Lipoprotein Lipase Deficiency · NA · recruiting

Other CENTOGENE GmbH Rostock trials

Trials by the same sponsor.

NCT06040008 — Investigating the Impact of Environmental Factors on the Transcriptomics Profile in Healthy Individuals · completed
NCT05075187 — Epidemiological Study in FRONtoTemporal Dementia · completed
NCT04925804 — Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) · completed
NCT04548921 — Biomarker for Friedreich's Ataxia (BioFridA) · unknown
NCT03866590 — Pyruvate Kinase Deficiency Epidemiological Study (PIECE) · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03198897 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by CENTOGENE GmbH Rostock
Last refreshed: 13 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03198897.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing