Last reviewed · How we verify
NCT03193580: AMPED
Accelerating Motor Learning in Pediatrics
NA trial testing Anodal Conventional tDCS in Healthy in 24 participants. Completed in 30 August 2018.
1 July 2018
Quick facts
| Lead sponsor | University of Calgary |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 24 |
| Start date | 1 July 2017 |
| Primary completion | 1 July 2018 |
| Estimated completion | 30 August 2018 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Anodal Conventional tDCS
- Anodal High Definition tDCS
- Sham tDCS
Conditions studied
- Healthy — all drugs for Healthy →
- Pediatrics — all drugs for Pediatrics →
Sponsor
University of Calgary
Who can join
Adults 12 to 18, any sex, with Healthy or Pediatrics. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Non-invasive brain stimulation can both study and potentially treat neurological disorders. Transcranial direct-current stimulation (tDCS) is an emerging safe and tolerability form of stimulation and has been used increasingly over the last decade. The purpose of this research is to see if two different types of tDCS can improve motor function in healthy children. tDCS has been shown to safely enhance hand motor function in healthy adults, and those that have suffered stroke and other conditions. Recently the investigators demonstrated that tDCS may enhance hand motor function in healthy children, however, how it does so is unknown. In addition to assessing changes in motor function when tDCS is given during motor skill training, the investigators will perform various tests before and after stimulation to understand the changes that happen in the brain accompanying motor skill learning and brain stimulation. The investigators hypothesize that there will be an accelerated acquisition of motor skill, when training is paired with conventional anodal tDCS, HD-tDCS, or sham tDCS.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Effects of High-Definition and Conventional Transcranial Direct-Current Stimulation on Motor Learning in Children.
Cole L, Giuffre A, Ciechanski P, Carlson HL, et al · · 2018 · cited 38× · PMID 30429768 · DOI 10.3389/fnins.2018.00787 -
Effects of Transcranial Direct Current Stimulation on GABA and Glx in Children: A pilot study.
Nwaroh C, Giuffre A, Cole L, Bell T, et al · · 2020 · cited 15× · PMID 31910218 · DOI 10.1371/journal.pone.0222620 -
Sensorimotor Robotic Measures of tDCS- and HD-tDCS-Enhanced Motor Learning in Children.
Cole L, Dukelow SP, Giuffre A, Nettel-Aguirre A, et al · · 2018 · cited 10× · PMID 30662456 · DOI 10.1155/2018/5317405 -
Effects of Transcranial Direct Current Stimulation and High-Definition Transcranial Direct Current Stimulation Enhanced Motor Learning on Robotic Transcranial Magnetic Stimulation Motor Maps in Children.
Giuffre A, Zewdie E, Wrightson JG, Cole L, et al · · 2021 · cited 4× · PMID 34690726 · DOI 10.3389/fnhum.2021.747840 -
Robotic mapping of motor cortex in children with perinatal stroke and hemiparesis.
Kuo HC, Zewdie E, Giuffre A, Gan LS, et al · · 2022 · cited 1× · PMID 35451540 · DOI 10.1002/hbm.25881
Verify or expand the search:
- PubMed search for NCT03193580
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03193580 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Calgary
- Last refreshed: 22 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03193580.
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