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NCT03193255
Efficacy and Safety of cleadewGP for Rigid Contact Lenses
NA trial testing OPHTECS cleadew GP in Contact Lens Solution Toxicity in 80 participants. Completed in 1 August 2019.
1 August 2019
Quick facts
| Lead sponsor | The Hong Kong Polytechnic University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 14 June 2017 |
| Primary completion | 1 August 2019 |
| Estimated completion | 1 August 2019 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- OPHTECS cleadew GP
Conditions studied
- Contact Lens Solution Toxicity — all drugs for Contact Lens Solution Toxicity →
Sponsor
The Hong Kong Polytechnic University
Who can join
Adults 6 to 10, any sex, with Contact Lens Solution Toxicity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Multipurpose solutions (MPS) are the most commonly prescribed regimen to clean, disinfect and rinse rigid lenses. The preservatives used in MPS may cause hypersensitivity and the presence of quaternary ammonium compounds (QAC) may increase development of antiseptic resistance mediated by QAC resistance genes, thus lowering the efficacy of disinfection. Povidone-iodine (PVI) has been safely used as a disinfectant for ophthalmic operations and eye drops. The cleadew GP (Ophtecs, Japan) tested in the current study is a PVI based rigid lens disinfecting solutions which does not employ QAC. If its efficacy and safety can be confirmed in this study, it will be a good alternative rigid lens care regimen for children.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Investigation of effects of orthokeratology and povidone iodine disinfecting solution on the conjunctival microbiome using MALDI-TOF mass spectrometry.
Boost MV, Cheung SW, Cho P. · · 2021 · PMID 37846320 · DOI 10.1016/j.aopr.2022.100024
Verify or expand the search:
- PubMed search for NCT03193255
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03193255 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Hong Kong Polytechnic University
- Last refreshed: 16 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03193255.
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