Who is sponsoring NCT03191045?

NCT03191045 is sponsored by University of Nottingham.

What drugs are being tested in NCT03191045?

Interventions in NCT03191045: MRI and concomitant perfused manometry of bowel motility.

Is NCT03191045 still recruiting?

NCT03191045 is currently completed. Last updated 17 January 2019.

Last reviewed 2019-01-17 · How we verify

NCT03191045: iPD1

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

In Vivo Predictive Dissolution 1

Completed Last updated 17 January 2019

What this trial tests

trial testing MRI and concomitant perfused manometry of bowel motility in Healthy in 20 participants. Completed in 1 March 2018.

Timeline

19 July 2017

Primary endpoint
1 March 2018

1 March 2018

Quick facts

Lead sponsor	University of Nottingham
Status	Completed
Study type	OBSERVATIONAL
Enrollment	20
Start date	19 July 2017
Primary completion	1 March 2018
Estimated completion	1 March 2018
Sites	1 location across United Kingdom

Drugs / interventions tested

MRI and concomitant perfused manometry of bowel motility

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

University of Nottingham

Who can join

Adults 18 to 60, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will: 1. validate MRI motility method with concomitant perfused manometry method in healthy adult participants. 2. measure exploratory endpoints of interest including GI fluid volumes in 21 adult healthy volunteers studied twice.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Will MRI of gastrointestinal function parallel the clinical success of cine cardiac MRI?
Hoad C, Clarke C, Marciani L, Graves MJ, et al · · 2019 · cited 11× · PMID 30299989 · DOI 10.1259/bjr.20180433
Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants.
Heissam K, Abrehart N, Hoad CL, Wright J, et al · · 2020 · cited 7× · PMID 33175860 · DOI 10.1371/journal.pone.0241441

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03191045 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Nottingham
Last refreshed: 17 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03191045.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing