Who is sponsoring NCT03189368?

NCT03189368 is sponsored by National and Kapodistrian University of Athens.

What drugs are being tested in NCT03189368?

Interventions in NCT03189368: Activation of multi-site pacing capability on CRT devices.

What condition does NCT03189368 study?

NCT03189368 studies Heart Failure.

Is NCT03189368 still recruiting?

NCT03189368 is currently completed. Last updated 11 September 2020.

Last reviewed 2020-09-11 · How we verify

NCT03189368: HUMVEE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Heart Failure Study of Multi-site Pacing Effects on Ventriculoarterial Coupling

Completed Last updated 11 September 2020

What this trial tests

trial testing Activation of multi-site pacing capability on CRT devices in Heart Failure in 80 participants. Completed in 1 September 2020.

Timeline

18 September 2017

Primary endpoint
1 September 2020

1 September 2020

Quick facts

Lead sponsor	National and Kapodistrian University of Athens
Status	Completed
Study type	OBSERVATIONAL
Enrollment	80
Start date	18 September 2017
Primary completion	1 September 2020
Estimated completion	1 September 2020
Sites	1 location across Greece

Drugs / interventions tested

Activation of multi-site pacing capability on CRT devices

Conditions studied

Heart Failure — all drugs for Heart Failure →

Sponsor

National and Kapodistrian University of Athens

Who can join

18 and older, any sex, with Heart Failure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To perform a comparative study of multi-site left ventricular pacing and cardiac resynchronization therapy effects on ventriculoarterial coupling and energy efficiency of the failing heart

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Heart failure study of multipoint pacing effects on ventriculoarterial coupling: Rationale and design of the HUMVEE trial.
Chrysohoou C, Dilaveris P, Antoniou CK, Skiadas I, et al · · 2018 · cited 4× · PMID 29034563 · DOI 10.1111/anec.12510
Multipoint left ventricular pacing effects on hemodynamic parameters and functional status: HUMVEE single-arm clinical trial (NCT03189368).
Antoniou CK, Dilaveris P, Chrysohoou C, Konstantinou K, et al · · 2022 · cited 3× · PMID 33677032 · DOI 10.1016/j.hjc.2021.02.012

Verify or expand the search:

Other recruiting trials for Heart Failure

Currently open trials in the same condition.

NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting

Other National and Kapodistrian University of Athens trials

Trials by the same sponsor.

NCT07295964 — Accuracy of Intraoral Scan Post-processing Methods: A Clinical Trial · NA · not yet recruiting
NCT07351981 — TcPRF for Knee Osteoarthritis · NA · enrolling by invitation
NCT07477496 — Recurrence and Anal Fistula Patient Reported Outcomes Trial · recruiting
NCT07295899 — Assessing the Influence of Implant Scanning Techniques on the Accuracy of Maxillary Complete-Arch Digital Scans for Impl · not yet recruiting
NCT06903130 — Clinical Study to Evaluate the Effects of the Complement C5 Inhibitor Ravulizumab on Serum Neurofilament Light Chain (sN · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03189368 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National and Kapodistrian University of Athens
Last refreshed: 11 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03189368.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing