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NCT03188744
Impact of Cancer Treatment on the Pelvic Floor Function in Survivors of Cervical Cancer
trial testing Assessment of the pelvic floor function in Cervical Cancer in 150 participants. Status unknown.
1 March 2019
Quick facts
| Lead sponsor | University of Sao Paulo |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 2 January 2019 |
| Primary completion | 1 March 2019 |
| Estimated completion | 1 June 2019 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Assessment of the pelvic floor function
- Questionnaire application
Conditions studied
- Cervical Cancer — all drugs for Cervical Cancer →
- Pelvic Floor Disorders — all drugs for Pelvic Floor Disorders →
- Surgery — all drugs for Surgery →
- Radiotherapy; Complications — all drugs for Radiotherapy; Complications →
Sponsor
University of Sao Paulo
Who can join
Eligibility, female only, with Cervical Cancer or Pelvic Floor Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Pelvic floor muscle dysfunctions (PFMD) represent an important public health problem that manifests itself through lower urinary tract symptoms (LUTS), anorectal and sexual dysfunction. PFMD is a common problem in cervical cancer survivors (CC) with a negative impact on quality of life (QoL). Objective: This study aims to evaluate the effect of oncological treatment on the function of pelvic floor muscles (PFM) of survivors of CC. Methods: Patients diagnosed with CC, of any stage, histology and degree, accompanied by the Oncology Gynecology Service of the Hospital das Clínicas of the Medical School of Ribeirão Preto at the University of São Paulo, will be studied in the period between 2004 and 2014. Four study groups will be formed: (1) Patients with CC with PFMD; (2) Patients with CC without PFMD; : (3) Patients without CC with PFMD; (2) Patients without CC without PFMD. Non-cancer patients will be recruited into the community. For the analysis of the prevalence of PFMD will be applied to the discomfort Questionnaire on pelvic floor (IDPE-20) for evaluation of pelvic organ prolapse (POP) complaints, anorectal symptoms and urinary incontinence, and the Sexual Questionnaire for urinary incontinence and pelvic organ prolapse (PISQ -12) for evaluation of sexual function. Both questionnaires have already been validated for the Portuguese language and are specific for women with PFMD. The pelvic floor impact questionnaire (PFIQ-7) will also be applied to assess the impact of PFMD on quality of life, daily living activities and emotional health. For the evaluation of general QOL, the EORTC questionnaire QLQ-C30 and its specific module for patients with CC, QLQ-CX24 will be used. The evaluation of PFM function will include vaginal palpation (Modified Oxford Scale) and perineometry (Peritron).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03188744 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
- Last refreshed: 20 December 2018
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