Who is sponsoring NCT03172533?

NCT03172533 is sponsored by University of Erlangen-Nürnberg Medical School.

What drugs are being tested in NCT03172533?

Interventions in NCT03172533: ethinyl estradiol 0.03mg and dienogest 2 mg (combination), Placebo oral capsule.

What condition does NCT03172533 study?

NCT03172533 studies Anorexia Nervosa.

Is NCT03172533 still recruiting?

NCT03172533 is currently terminated. Last updated 30 January 2019.

Last reviewed 2019-01-30 · How we verify

NCT03172533: HOSAN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Estrogen Replacement in Anorexia Nervosa

Terminated Phase 2 Last updated 30 January 2019

What this trial tests

Phase 2 trial testing ethinyl estradiol 0.03mg and dienogest 2 mg (combination) in Anorexia Nervosa in 11 participants. Terminated before completion.

Timeline

15 March 2016

Primary endpoint
15 January 2019

15 January 2019

Quick facts

Lead sponsor	University of Erlangen-Nürnberg Medical School
Phase	Phase 2
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	11
Start date	15 March 2016
Primary completion	15 January 2019
Estimated completion	15 January 2019
Sites	1 location across Germany

Drugs / interventions tested

ethinyl estradiol 0.03mg and dienogest 2 mg (combination) — full drug profile →
Placebo oral capsule

Conditions studied

Anorexia Nervosa — all drugs for Anorexia Nervosa →

Sponsor

University of Erlangen-Nürnberg Medical School

Who can join

Adults 18 to 45, female only, with Anorexia Nervosa. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The present study is a placebo-controlled randomised study on the effects of estrogen replacement upon AN-associated psychopathology, several neurocognitive domains and appetite-regulating circuits in female patients with AN. The investigators aim at assessing peripheral concentrations of neuroendocrinological components of the Hypothalamus-Pituitary-Gonadal (HPG) and Hypothalamus-Pituitary-Adrenal (HPA) axis, as well as appetite-regulating hormones in AN and to examine associations with AN-associated psychopathology and neurocognitive performances before (baseline), during and after inpatient psychotherapy of female patients receiving concomitant treatment with estrogens (vs. placebo).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Prospective, randomized, double-blind, placebo-controlled phase IIa clinical trial on the effects of an estrogen-progestin combination as add-on to inpatient psychotherapy in adult female patients suffering from anorexia nervosa.
Paslakis G, Maas S, Gebhardt B, Mayr A, et al · · 2018 · cited 5× · PMID 29631553 · DOI 10.1186/s12888-018-1683-1

Verify or expand the search:

Other recruiting trials for Anorexia Nervosa

Currently open trials in the same condition.

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Other University of Erlangen-Nürnberg Medical School trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03172533 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Erlangen-Nürnberg Medical School
Last refreshed: 30 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03172533.

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