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NCT03171727
Low Molecular Weight Heparin for the Prevention of Early TIPS Dysfunction
NA trial testing low molecular weight heparin in Liver Cirrhosis in 117 participants. Status unknown.
15 May 2019
Quick facts
| Lead sponsor | West China Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 117 |
| Start date | 1 June 2017 |
| Primary completion | 15 May 2019 |
| Estimated completion | 30 December 2019 |
| Sites | 1 location across China |
Drugs / interventions tested
- low molecular weight heparin — full drug profile →
Conditions studied
- Liver Cirrhosis — all drugs for Liver Cirrhosis →
- Portal Hypertension — all drugs for Portal Hypertension →
Sponsor
West China Hospital
Who can join
Adults 18 to 75, any sex, with Liver Cirrhosis or Portal Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Transjugular intrahepatic portosystemic shunt (TIPS) dysfunction is defined as a loss of decompression of the portal venous system due to occlusion or stenosis of the TIPS. Occlusion of the TIPS can either be due to thrombosis or hyperplasia of the intima. Thrombosis of the TIPS usually occurs early and can happen within 24 hours of TIPS creation. The frequency of this complication is on the order of 10%-15% when bare stents are used. Post-TIPS short-term low molecular weight heparin (LMWH) was used to prevent the early thrombosis formation. Weather post-TIPS LMWH was necessary when polytetrafluoroethylene-covered stent was used during TIPS creation was not answered. The present study was designed to evaluate the effect of short-term use of LMWH on early TIPS dysfunction.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03171727
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Related trials
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Other recruiting trials for Liver Cirrhosis
Currently open trials in the same condition.
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Other West China Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03171727 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by West China Hospital
- Last refreshed: 8 January 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03171727.
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