NCT03168789 is a NA clinical trial of Tension Tamer (TT) in Pre-hypertension, sponsored by Medical University of South Carolina.

Who is sponsoring NCT03168789?

NCT03168789 is sponsored by Medical University of South Carolina.

What drugs are being tested in NCT03168789?

Interventions in NCT03168789: Tension Tamer (TT), Lifestyle education program (SPCTL).

What condition does NCT03168789 study?

NCT03168789 studies Pre-hypertension.

Is NCT03168789 still recruiting?

NCT03168789 is currently completed. Last updated 14 January 2020.

Last reviewed 2020-01-14 · How we verify

NCT03168789

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Tension Tamer Randomized Control Trial

Completed NA Last updated 14 January 2020

What this trial tests

NA trial testing Tension Tamer (TT) in Pre-hypertension in 80 participants. Completed in 22 November 2019.

Timeline

1 October 2016

Primary endpoint
22 November 2019

22 November 2019

Quick facts

Lead sponsor	Medical University of South Carolina
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	80
Start date	1 October 2016
Primary completion	22 November 2019
Estimated completion	22 November 2019
Sites	1 location across United States

Drugs / interventions tested

Tension Tamer (TT)
Lifestyle education program (SPCTL)

Conditions studied

Pre-hypertension — all drugs for Pre-hypertension →

Sponsor

Medical University of South Carolina

Who can join

Adults 18 to 90, any sex, with Pre-hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is 12 months long and consists of 5 visits at baseline, months 1, 3, 6, and 12. To determine eligibility potential subjects will have resting blood pressures (BP) measured on 2 occasions. Pre-hypertensive individuals will be invited to participate in the study. After informed consent is obtained, subjects will complete baseline visit consisting of a survey, resting BP, wear activity watch for 7 days ambulatory blood pressure monitor for 24-hours, collect saliva and urine samples. Subjects will then be randomly assigned to Tension Tamer (TT) or lifestyle education program delivered via smartphone (SPCTL) groups. At the remaining 4 visits subjects will again complete a survey, resting BP, wear activity watch for 7 days ambulatory blood pressure monitor for 24-hours, collect saliva and urine samples. Throughout the 12 months TT group will meditate twice daily and SPCTL group will log physical activity.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Meditation smartphone application effects on prehypertensive adults' blood pressure: Dose-response feasibility trial.
Adams ZW, Sieverdes JC, Brunner-Jackson B, Mueller M, et al · · 2018 · cited 26× · PMID 30010353 · DOI 10.1037/hea0000584
Impact of 12-Month Smartphone Breathing Meditation Program upon Systolic Blood Pressure among Non-Medicated Stage 1 Hypertensive Adults.
Chandler J, Sox L, Diaz V, Kellam K, et al · · 2020 · cited 17× · PMID 32192020 · DOI 10.3390/ijerph17061955
The Recent Advances of Mobile Healthcare in Cardiology Practice.
Kulbayeva S, Tazhibayeva K, Seiduanova L, Smagulova I, et al · · 2022 · cited 5× · PMID 36311150 · DOI 10.5455/aim.2022.30.236-250

Verify or expand the search:

Other recruiting trials for Pre-hypertension

Currently open trials in the same condition.

NCT05892328 — Watermelon Dose Response Blood Pressure Study · NA · active not recruiting

Other Medical University of South Carolina trials

Trials by the same sponsor.

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NCT07149207 — Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors · Phase 2 · recruiting
NCT06148038 — CBD for Breast Cancer Primary Tumors · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03168789 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of South Carolina
Last refreshed: 14 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03168789.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing