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NCT03167476

Comparative Study of microRNA Changes in Patients With Reactive Lymphoid Hyperplasia and Malignant Lymphoma

Status unknown Last updated 30 May 2017
What this trial tests

trial in Lymphoma in 200 participants. Status unknown.

Timeline
1 August 2016
Primary endpoint
1 December 2017
1 December 2018

Quick facts

Lead sponsorUniversity of Electronic Science and Technology of China
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment200
Start date1 August 2016
Primary completion1 December 2017
Estimated completion1 December 2018
Sites1 location across China

Conditions studied

Sponsor

University of Electronic Science and Technology of China

Who can join

18 and older, any sex, with Lymphoma or Hyperplasia Lymphoid Reactive. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objectives are to: 1. validate a panel of tissue-specific miRNAs that are differentially expressed in the tissue of patients with and without reactive hyperplasia and lymphoma. 2. investigate the physiological range of the miRNA panel in lymphoma and reactive hyperplasia subjects. 3. investigate the dysregulation of miRNA panel and their prognostic and predictive values in clinical outcomes to identifying patients with malignant lymphoma or reactive hyperplasia. The objectives are to: 1. validate a panel of tissue-specific miRNAs that are differentially expressed in the tissue of patients with and without reactive hyperplasia and lymphoma. 2. investigate the physiological range of the miRNA panel in lymphoma and reactive hyperplasia subjects. 3. investigate the dysregulation of miRNA panel and their prognostic and predictive values in clinical outcomes to identifying patients with malignant lymphoma or reactive hyperplasia. This trial involves tissue samples diagnosed as lymphoma and reactive hyperplasia. The investigators will develop panels of miRNAs that are specific biomarkers of lymphoma, and assist clinical outcomes with these miRNAs.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Targeting miRNAs and Other Non-Coding RNAs as a Therapeutic Approach: An Update.
    Bayraktar E, Bayraktar R, Oztatlici H, Lopez-Berestein G, et al · · 2023 · cited 51× · PMID 37104009 · DOI 10.3390/ncrna9020027

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Other recruiting trials for Lymphoma

Currently open trials in the same condition.

Other University of Electronic Science and Technology of China trials

Trials by the same sponsor.

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