NCT03167372

Pilot Comparison of N-of-1 Trials of Light Therapy

Completed NA Last updated 25 June 2019

What this trial tests

NA trial testing Litebook® Advantage in Cancer in 15 participants. Completed in 31 December 2018.

Timeline

6 September 2017

Primary endpoint
31 December 2018

31 December 2018

Quick facts

Lead sponsor	Columbia University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	15
Start date	6 September 2017
Primary completion	31 December 2018
Estimated completion	31 December 2018
Sites	1 location across United States

Drugs / interventions tested

• Litebook® Advantage
• Fitbit Flex2 TM

Conditions studied

• Cancer — all drugs for Cancer →
• Health Behavior — all drugs for Health Behavior →
• Depression — all drugs for Depression →

Sponsor

Columbia University

Who can join

21 and older, any sex, with Cancer or Health Behavior. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study compares the effect of two N-of-1 trials on study compliance with an N-of-1 protocol and on satisfaction with participation in an N-of-1 trial. Using within-person analyses, the study also compares the effect of different types of light therapy on mood, fatigue, sleep, physical activity, and side effects within a mild to moderately depressed cancer survivor population. Ten participants will be randomized to the bright white versus dim red light therapy N-of-1 trial, while the remaining 5 participants will be randomized to a dim white versus dim red light comparator N-of-1 trial.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. A within-subject comparison of the effect of two putative sham light therapies on mood and fatigue in cancer survivors: Results from a series of N-of-1 trials.
   Shechter A, Julian J, Davidson KW, Cheung K, et al · · 2019 · cited 2× · PMID 31014829 · DOI 10.1016/j.psychres.2019.04.018