Who is sponsoring NCT03161119?

NCT03161119 is sponsored by Istituto Clinico Humanitas.

What drugs are being tested in NCT03161119?

Interventions in NCT03161119: Ultrasound guided embryotransfer with Cook K-Jets-551910-S, Ultrasound guided embryotransfer with Cook k-soft-5000 (or K-J-SP-681710 and K-J-SPPE-681710).

What condition does NCT03161119 study?

NCT03161119 studies Infertility.

Is NCT03161119 still recruiting?

NCT03161119 is currently status unknown. Last updated 21 March 2019.

Last reviewed 2019-03-21 · How we verify

NCT03161119: CATH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparing Two Different Embryo Transfer Catheters

Status unknown NA Last updated 21 March 2019

What this trial tests

NA trial testing Ultrasound guided embryotransfer with Cook K-Jets-551910-S in Infertility in 352 participants. Status unknown.

Timeline

26 September 2017

Primary endpoint
1 June 2019

1 December 2019

Quick facts

Lead sponsor	Istituto Clinico Humanitas
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	352
Start date	26 September 2017
Primary completion	1 June 2019
Estimated completion	1 December 2019
Sites	1 location across Italy

Drugs / interventions tested

Ultrasound guided embryotransfer with Cook K-Jets-551910-S
Ultrasound guided embryotransfer with Cook k-soft-5000 (or K-J-SP-681710 and K-J-SPPE-681710)

Conditions studied

Infertility — all drugs for Infertility →

Sponsor

Istituto Clinico Humanitas

Who can join

Adults 18 to 38, female only, with Infertility. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Numerous published trials now document that the embryo transfer (ET) procedure has a huge impact on pregnancy and delivery rates after IVF (In Vitro Fertilization). To compare the ease of use (defined as the rate of successful atraumatic insertion) of different types of embryo transfer (ET) catheters. This prospective randomized unblinded controlled clinical trial is performed to determine if there is any difference in ease of use among 2 different catheters : Cook k-soft-5000, Cook K-JETS-551910-S. Inclusion criteria: patients \< / = 38 years of age, body mass index (BMI) between 18 and 28, at least one frozen-thawed blastocyst transferred. Exclusion criteria: ICSI (Intracytoplasmic Sperm Injection)-TESE (Testicular Sperm Extraction) IVF cycles. A number of 352 consecutive women undergoing embryo transfer will be selected for this prospective, randomized controlled trial. Two protocols for endometrial preparation will be used before frozen/thawed blastocyst transfer: the modified spontaneous protocol and the oral/transdermal preparation protocol. ET will be done with patient in lithotomy position, under ultrasound guidance. No anesthesia will be used for the procedure. 176 patients will be enrolled in this trial and randomized to enter one of the two catheter group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

One step further: randomised single-centre trial comparing the direct and afterload techniques of embryo transfer.
Levi Setti PE, Cirillo F, Morenghi E, Immediata V, et al · · 2021 · cited 7× · PMID 34323282 · DOI 10.1093/humrep/deab178

Verify or expand the search:

Other recruiting trials for Infertility

Currently open trials in the same condition.

NCT07074015 — IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Speci · NA · recruiting
NCT07358468 — Impact Of FET Preparation Protocol On Endometrial Peristalsis: A Prospective Cohort Study · recruiting
NCT07340827 — A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH · Phase 3 · recruiting
NCT07369362 — To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That · NA · active not recruiting
NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting

Other Istituto Clinico Humanitas trials

Trials by the same sponsor.

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NCT07362342 — RIght VEntricle Response to Major Lung Resection in VATS and Robotic Surgery · not yet recruiting
NCT07346274 — Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy. · enrolling by invitation
NCT07491419 — The Impact of Fast Antimicrobial Sensitivity Testing Tools on Stewardship Antibiotic and Clinical Outcome (ACT-FAST) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03161119 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istituto Clinico Humanitas
Last refreshed: 21 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03161119.

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