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NCT03156348

Impact of Clinical Pharmacist on Adverse Drug Events in Older Adults

Status unknown NA Last updated 17 May 2017
What this trial tests

NA trial testing Clinical Pharmacist Care in Drug-Related Side Effects and Adverse Reactions in 611 participants. Status unknown.

Timeline
2 May 2015
Primary endpoint
22 September 2017
22 December 2017

Quick facts

Lead sponsorUniversity of Chile
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposeprevention
Enrollment611
Start date2 May 2015
Primary completion22 September 2017
Estimated completion22 December 2017
Sites1 location across Chile

Drugs / interventions tested

Conditions studied

Sponsor

University of Chile

Who can join

60 and older, any sex, with Drug-Related Side Effects and Adverse Reactions. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Adverse drug events (ADE) are one of the major problems affecting quality of care and achievement of therapeutic goals in older adults (OA), increasing re-admissions, hospital stays, resource use, and problems on patient safety. The present study aim is to determine the impact of the clinical pharmacist interventions on the prevention of ADE in OA at 3 months post-discharge compared to usual care. A randomized clinical trial of two parallel groups 1: 1 (control and intervention) plus a historical control group will be carried out at the Internal Medicine Service (IMS) of the teaching Hospital at the University of Chile. The sample will be of 611 patients (242 per each parallel group and 127 of the historical control group) of 60 years or older, admitted to the IMS for acute pathology or decompensation of chronic pathology, with survival over 6 months, who is under pharmacological therapy and have a caretaker or responsible contact person at discharge. The historical control group will receive usual care and the parallel control group will also receive training on pharmacogeriatrics. The intervention group will receive the care of a clinical pharmacist during hospitalization, at discharge and post-discharge, through a home visit at 30 days post-discharge and a telephone call at 60 days post discharge.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Interventions to improve the appropriate use of polypharmacy for older people.
    Rankin A, Cadogan CA, Patterson SM, Kerse N, et al · · 2018 · cited 265× · PMID 30175841 · DOI 10.1002/14651858.cd008165.pub4
  2. Interventions for improving medication-taking ability and adherence in older adults prescribed multiple medications.
    Cross AJ, Elliott RA, Petrie K, Kuruvilla L, et al · · 2020 · cited 135× · PMID 32383493 · DOI 10.1002/14651858.cd012419.pub2
  3. Interventions to improve the appropriate use of polypharmacy for older people.
    Cole JA, Gonçalves-Bradley DC, Alqahtani M, Barry HE, et al · · 2023 · cited 50× · PMID 37818791 · DOI 10.1002/14651858.cd008165.pub5
  4. Medication review in hospitalised patients to reduce morbidity and mortality.
    Bülow C, Clausen SS, Lundh A, Christensen M. · · 2023 · cited 37× · PMID 36688482 · DOI 10.1002/14651858.cd008986.pub4

Verify or expand the search:

Other recruiting trials for Drug-Related Side Effects and Adverse Reactions

Currently open trials in the same condition.

Other University of Chile trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing