NCT03151759 (MMP-7) is a clinical trial of Neoadjuvant radiotherapy in Rectal Cancer, sponsored by Region Skane.

Who is sponsoring NCT03151759?

NCT03151759 is sponsored by Region Skane.

What drugs are being tested in NCT03151759?

Interventions in NCT03151759: Neoadjuvant radiotherapy.

What condition does NCT03151759 study?

NCT03151759 studies Rectal Cancer.

Is NCT03151759 still recruiting?

NCT03151759 is currently completed. Last updated 12 May 2017.

Last reviewed 2017-05-12 · How we verify

NCT03151759: MMP-7

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients

Completed Last updated 12 May 2017

What this trial tests

trial testing Neoadjuvant radiotherapy in Rectal Cancer in 77 participants. Completed in 16 March 2007.

Timeline

6 November 2002

Primary endpoint
16 March 2007

16 March 2007

Quick facts

Lead sponsor	Region Skane
Status	Completed
Study type	OBSERVATIONAL
Enrollment	77
Start date	6 November 2002
Primary completion	16 March 2007
Estimated completion	16 March 2007

Drugs / interventions tested

Neoadjuvant radiotherapy

Conditions studied

Rectal Cancer — all drugs for Rectal Cancer →

Sponsor

Region Skane — full company profile →

Who can join

Eligibility, any sex, with Rectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To analyse the effects of radiation therapy on inflammation and matrilysin levels in rectal cancer patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

MMP7 Modulation by Short- and Long-term Radiotherapy in Patients with Rectal Cancer.
Stene C, Polistena A, Gaber A, Nodin B, et al · · 2018 · cited 6× · PMID 29275310 · DOI 10.21873/invivo.11215
Multi-Platform Detection of MMP-7 in Colorectal Carcinoma.
Večurkovská I, Stupák M, Kaťuchová J, Roškovičová V, et al · · 2026 · PMID 41595135 · DOI 10.3390/cancers18020214

Verify or expand the search:

Other trials of Neoadjuvant radiotherapy

Trials testing the same drug.

NCT06769919 — A Randomized Controlled Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined with Systemic Therapy for · Phase 2, PHASE3 · not yet recruiting
NCT06472752 — Neoadjuvant Radiotherapy for High-risk UTUC · not yet recruiting
NCT06313073 — Neoadjuvant Radiotherapy for Breast Cancer · NA · unknown
NCT05992870 — Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction · NA · recruiting
NCT05216900 — Breast Reconstruction and Neoadjuvant Radiotherapy · NA · recruiting

Other recruiting trials for Rectal Cancer

Currently open trials in the same condition.

NCT07528209 — Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer · Phase 3 · recruiting
NCT07537998 — Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a · Phase 2, PHASE3 · recruiting
NCT07501845 — Registry Maastro Applicator · recruiting
NCT07369531 — The Impact of Two-Stage Turnbull-Cutait Pull-Through Coloanal Anastomosis on Stoma-free Survival in Low Rectal Anal-pres · NA · recruiting
NCT07505472 — Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Wit · Phase 2, PHASE3 · recruiting

Other Region Skane trials

Trials by the same sponsor.

NCT07511673 — The Study is a Randomised Clinical Trial (RCT) to Test if Preoperative Dental Screening is Superior to no Preoperative D · NA · not yet recruiting
NCT07169747 — Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young · Phase 2 · recruiting
NCT07494669 — Proteomics and Physiological Parameters Predicting Complications After Colorectal Cancer Surgery · not yet recruiting
NCT07462351 — System-integrated Point-of-Care Ultrasound in Breast Cancer Screening · NA · recruiting
NCT06975696 — Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03151759 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Region Skane
Last refreshed: 12 May 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03151759.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing