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NCT03148574
Intrauterine Misoprostol Versus Intravenous Oxytocin Infusion During Cesarean Delivery
Phase 3 trial testing Misoprostol in Post Partum Hemorrhage in 240 participants. Completed in 15 December 2019.
15 September 2019
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 240 |
| Start date | 2 July 2017 |
| Primary completion | 15 September 2019 |
| Estimated completion | 15 December 2019 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Misoprostol (Misoprostol) — full drug profile →
- Oxytocin (OXYTOCIN) — full drug profile →
Conditions studied
- Post Partum Hemorrhage — all drugs for Post Partum Hemorrhage →
Sponsor
Assiut University
Who can join
Eligibility, female only, with Post Partum Hemorrhage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Bleeding is still the major cause of mortality and morbidity in postpartum period. World health organization has reported 585000 deaths for pregnancy each year. Twenty five percent of cases die from post-partum bleeding. Mean amount of blood lost is 500 ml during normal vaginal delivery, 1000 ml in cesarean section, and 3500 ml during cesarean section with emergency hysterectomy
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03148574
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Misoprostol
Trials testing the same drug.
- NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
- NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
- NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
- NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
- NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
Other recruiting trials for Post Partum Hemorrhage
Currently open trials in the same condition.
- NCT05488457 — Oxytocin Pharmacokinetics and Pharmacodynamics · Phase 2 · recruiting
- NCT06604325 — Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery. · NA · recruiting
- NCT06577922 — Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in Nepal · NA · recruiting
- NCT05370820 — Prevention of Postpartum Hemorrhage With Tranexamic Acid · Phase 2 · recruiting
Other Assiut University trials
Trials by the same sponsor.
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- NCT07234526 — Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients · not yet recruiting
- NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
- NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03148574 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 23 April 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03148574.
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