Last reviewed · How we verify
NCT03147170
A Biomarker to Detect Salt Sensitivity
trial testing High and low salt diets in Hypertension Uncomplicated in 30 participants. Completed in 31 December 2018.
30 June 2018
Quick facts
| Lead sponsor | University of Minnesota |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 1 January 2016 |
| Primary completion | 30 June 2018 |
| Estimated completion | 31 December 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- High and low salt diets
Conditions studied
- Hypertension Uncomplicated — all drugs for Hypertension Uncomplicated →
- Pre Hypertension — all drugs for Pre Hypertension →
Sponsor
University of Minnesota
Who can join
Adults 30 to 75, any sex, with Hypertension Uncomplicated or Pre Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators are proposing that individuals with elevated levels of NT-proBNP are resistant to natriuretic peptides and are unable to handle sodium loads and maintain optimal blood pressure values.The investigators will test this hypothesis by comparing the blood pressure response to low and high salt diets in individuals with pre- or hypertension and who have normal or elevated levels of NT-proBNP. The investigators expect that blood pressure values in those with normal levels of NT-proBNP will not change with high salt diets, whereas, in those with elevated levels of NT-proBNP, blood pressure values will increase significantly when exposed to high salt diets.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03147170
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03147170 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Minnesota
- Last refreshed: 18 April 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03147170.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing