Last reviewed · How we verify
NCT03146130: NoISE-PD
Study of the Efficacy of N-acetylcysteine (NAC) on Impulse Control Disorders
Phase 3 trial testing Variation of behaviors of Parkinson's disease in Impulse Control Disorder in 70 participants. Status unknown.
20 December 2019
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire, Amiens |
|---|---|
| Phase | Phase 3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 5 July 2018 |
| Primary completion | 20 December 2019 |
| Estimated completion | 20 December 2019 |
| Sites | 1 location across France |
Drugs / interventions tested
- Variation of behaviors of Parkinson's disease — full drug profile →
Conditions studied
- Impulse Control Disorder — all drugs for Impulse Control Disorder →
- Parkinson — all drugs for Parkinson →
Sponsor
Centre Hospitalier Universitaire, Amiens
Who can join
18 and older, any sex, with Impulse Control Disorder or Parkinson. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Impulse control disorders encountered in Parkinson's disease (PD) are induced by dopaminergic medications and their frequency is estimated to be nearly 20%, mainly under dopaminergic agonists (AD).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Overview on the Effects of <i>N</i>-Acetylcysteine in Neurodegenerative Diseases.
Tardiolo G, Bramanti P, Mazzon E. · · 2018 · cited 197× · PMID 30551603 · DOI 10.3390/molecules23123305
Verify or expand the search:
- PubMed search for NCT03146130
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Impulse Control Disorder
Currently open trials in the same condition.
- NCT06639594 — Feasibility of Accelerated, Personalized rTMS as an Adjuvant for Impulse Control Disorders: a Pilot Study · Phase 1 · recruiting
- NCT06561919 — STIMPulseControl Ancillary Speech Study · NA · recruiting
- NCT06485986 — Frontosubthalamic Networks in Parkinson's Disease. · NA · recruiting
- NCT05712057 — Neurostimulation Versus Therapy for Problems With Emotions · NA · recruiting
Other Centre Hospitalier Universitaire, Amiens trials
Trials by the same sponsor.
- NCT07354568 — Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock · recruiting
- NCT07071662 — Induction of Labor in Breech Presentation · completed
- NCT06909487 — Clinical Characterization of Very and Extremely Preterm Infants Who Received Excess Erythrocyte Transfusions With Respec · completed
- NCT07037719 — Automatic Detection of Eligible Patients to RAUC Protocol (RAUCISABLE) · recruiting
- NCT06996145 — Study of the Isometry of the Anterior Cruciate Ligament From the Center of the Native MRI Insertion Reported on Dynamic · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03146130 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire, Amiens
- Last refreshed: 6 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03146130.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing