NCT03144336: MOTIVES

Using Mobile Technology and Incentives With Men Who Have Sex With Men and Transgender Women for HIV Prevention

Completed NA Last updated 10 September 2019

What this trial tests

NA trial testing Information provision in HIV Infections in 217 participants. Completed in 23 August 2019.

Timeline

24 May 2017

Primary endpoint
23 August 2019

23 August 2019

Quick facts

Lead sponsor	RAND
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	217
Start date	24 May 2017
Primary completion	23 August 2019
Estimated completion	23 August 2019
Sites	1 location across United States

Drugs / interventions tested

• Information provision
• Weekly quizzes
• Rewards for testing HIV-negative

Conditions studied

• HIV Infections — all drugs for HIV Infections →
• HIV — all drugs for HIV →

Sponsor

RAND — full company profile →

Who can join

18 and older, any sex, with HIV Infections or HIV. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This project called Mobile Technology and Incentives (MOTIVES) aims to increase engagement with HIV prevention information and improve testing frequency among Latino/a men who have sex with men (MSM) and transgender women (TGW). Its primary goal is to develop and test the feasibility and acceptability of an HIV prevention intervention that uses text messages in combination with prizes to improve HIV prevention information retention and HIV testing frequency. The project will be conducted in collaboration with Bienestar Human Services, Inc. (Bienestar) in Los Angeles County. Phase 1 consists of formative research (focus groups n=9) with MSM (n=52) and TGW (n=39) to complement the previously collected pilot data (2014-2015) to finalize the planned intervention. In Phase 2, the intervention will be piloted among 5 individuals, implemented, and tested in a small, randomized controlled trial (RCT) among 200 Latino MSM and TGW from Bienestar's HIV testing sites. Interested individuals will be screened for eligibility upon testing HIV-negative (those testing positive will be linked to HIV services as required by Bienestar's standard of care). Eligible participants will be randomized into either the intervention or control group that will both receive study information weekly and will be invited to get tested for HIV every three months. Participants in the intervention group will be able to accumulate rewards points for correctly answering weekly quizzes regarding the HIV prevention information; these reward incentives aim to encourage retention in the study and improve HIV prevention knowledge engagement and recollection. Every three months those in the intervention group can win a prize based on testing HIV-negative at least once during that time period. The chance of winning will increase based on the number of reward points a participant accumulates by correctly answering questions on the weekly quizzes. The primary outcome measures will include HIV-preventive knowledge and frequency of HIV testing (at least once every 3 months). In Phase 3 of the study, the investigators will conduct 6 focus groups with approximately 5-8 participants each among MSM (n=3) and TGW (n=1) study participants, testing site staff (n=1), and administrative staff (n=1) to identify implementation challenges and areas for improvement; and estimate mission-critical design parameters with point and confidence interval estimates to inform a subsequent, fully-powered R01 application.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Behavioral economics-based incentives supported by mobile technology on HIV knowledge and testing frequency among Latino/a men who have sex with men and transgender women: Protocol for a randomized pilot study to test intervention feasibility and acceptability.
   Linnemayr S, MacCarthy S, Kim A, Giguere R, et al · · 2018 · cited 25× · PMID 30290851 · DOI 10.1186/s13063-018-2867-1
2. The acceptability and feasibility of a pilot study examining the impact of a mobile technology-based intervention informed by behavioral economics to improve HIV knowledge and testing frequency among Latinx sexual minority men and transgender women.
   MacCarthy S, Mendoza-Graf A, Wagner Z, L Barreras J, et al · · 2021 · cited 12× · PMID 33579242 · DOI 10.1186/s12889-021-10335-5
3. Brief Report: Using Behavioral Economics to Increase HIV Knowledge and Testing Among Latinx Sexual Minority Men and Transgender Women: A Quasi-Experimental Pilot Study.
   MacCarthy S, Wagner Z, Barreras JL, Kim A, et al · · 2020 · cited 12× · PMID 32931684 · DOI 10.1097/qai.0000000000002433