Who is sponsoring NCT03141125?

NCT03141125 is sponsored by Indonesia University.

What drugs are being tested in NCT03141125?

Interventions in NCT03141125: Physalis angulata ethanol extract, Placebo.

What condition does NCT03141125 study?

NCT03141125 studies Scleroderma.

Is NCT03141125 still recruiting?

NCT03141125 is currently completed. Last updated 27 August 2017.

Last reviewed 2017-08-27 · How we verify

NCT03141125

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Ethanol Extract Physalis Angulata Linn. in Scleroderma Patients With Standard Therapy to Reduce Skin Fibrosis Based on Modified Rodnan Skin Score, Reduce Inflammation, Immunological Response and Fibrosis

Completed NA Last updated 27 August 2017

What this trial tests

NA trial testing Physalis angulata ethanol extract in Scleroderma in 62 participants. Completed in 1 August 2017.

Timeline

1 January 2016

Primary endpoint
1 August 2017

1 August 2017

Quick facts

Lead sponsor	Indonesia University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	62
Start date	1 January 2016
Primary completion	1 August 2017
Estimated completion	1 August 2017
Sites	2 locations across Indonesia

Drugs / interventions tested

Physalis angulata ethanol extract
Placebo

Conditions studied

Scleroderma — all drugs for Scleroderma →

Sponsor

Indonesia University

Who can join

Adults 18 to 60, any sex, with Scleroderma. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Degree of skin fibrosis based on modified Rodnan Skin Score (mRSS)
Time frame: 3 months of intervention
Clinical improvement of skin fibrosis in scleroderma patients measured by modified Improvement in skin fibrosis is defined if there is a significant reduced of mRSS.

Sponsor's own description

Study about the effect of ethanol extract physalis angulate in scleroderma patients with standard therapy to reduce skin fibrosis based on modified Rodnan Skin Score, reduce inflammation, immunological response and fibrosis: A Randomized Clinical Placebo ControlledTrial with a prospective cohort study on scleroderma outpatient clinic in Cipto Mangunkusumo Hospital in Jakarta and Hasan Sadikin Hospital in Bandung, from January 2016 to July 2017

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Upcoming treatments for morphea.
Wenzel D, Haddadi NS, Afshari K, Richmond JM, et al · · 2021 · cited 20× · PMID 34272836 · DOI 10.1002/iid3.475

Verify or expand the search:

Other recruiting trials for Scleroderma

Currently open trials in the same condition.

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NCT06554132 — Respiratory Muscle Strength and Aerobic Capacity in Scleroderma · recruiting
NCT03800017 — Skeletal Muscle Function in Interstitial Lung Disease · NA · recruiting
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Other Indonesia University trials

Trials by the same sponsor.

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NCT07420335 — Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy · NA · not yet recruiting
NCT07278284 — The Effectiveness of Press Needle Acupuncture on Preoperative Anxiety in Tympanoplasty and Mastoidectomy · NA · recruiting
NCT07337187 — Effect of Thread-Embedding Acupuncture at EX-B2 on Pain and Quality of Life in Chronic Low Back Pain · NA · not yet recruiting
NCT07242001 — Laser Acupuncture for Otitis Media With Effusion in Children · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03141125 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indonesia University
Last refreshed: 27 August 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03141125.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing