Who is sponsoring BOX?

BOX is sponsored by Jesper Kjaergaard.

What condition does BOX study?

BOX studies Out-of-Hospital Cardiac Arrest, Blood Pressure, Hemodynamic Instability.

What drugs are being tested in BOX?

Interventions: Low normal MAP, High normal MAP, Low normal PaO2., High normal PaO2.

Last reviewed 2022-06-30 · How we verify

Blood Pressure and OXygenation Targets After OHCA (BOX)

NCT03141099 NA COMPLETED

This study compares two blood pressure targets and two oxygenation targets in the post-resuscitation care of comatose out-of-hospital cardiac arrets patients. Using a novel method the blood pressure-intervention is double-blinded. The oxygenation-intervention is open-label. As a subordinate study, the patients will be randomized 1:1 to active fever-control with an automated feedback temperature control-device for 36 or 72 hours following return of spontaneous circulation.

Details

Lead sponsor	Jesper Kjaergaard
Phase	NA
Status	COMPLETED
Enrolment	802
Start date	Fri Mar 10 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Tue Mar 15 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Out-of-Hospital Cardiac Arrest
Blood Pressure
Hemodynamic Instability

Interventions

Low normal MAP
High normal MAP
Low normal PaO2.
High normal PaO2

Countries

Denmark