NCT03140904 is a NA clinical trial of Standard weekly visits in Severe Acute Malnutrition, sponsored by Epicentre.

Who is sponsoring NCT03140904?

NCT03140904 is sponsored by Epicentre.

What drugs are being tested in NCT03140904?

Interventions in NCT03140904: Standard weekly visits, Monthly visits.

What condition does NCT03140904 study?

NCT03140904 studies Severe Acute Malnutrition.

Is NCT03140904 still recruiting?

NCT03140904 is currently completed. Last updated 12 May 2020.

Last reviewed 2020-05-12 · How we verify

NCT03140904

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Reducing the Frequency of Follow up and Task Sharing in the Treatment of Uncomplicated Severe Acute Malnutrition

Completed NA Last updated 12 May 2020

What this trial tests

NA trial testing Standard weekly visits in Severe Acute Malnutrition in 3,945 participants. Completed in 27 April 2020.

Timeline

23 January 2018

Primary endpoint
30 November 2019

27 April 2020

Quick facts

Lead sponsor	Epicentre
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	3,945
Start date	23 January 2018
Primary completion	30 November 2019
Estimated completion	27 April 2020
Sites	1 location across Nigeria

Drugs / interventions tested

Standard weekly visits
Monthly visits

Conditions studied

Severe Acute Malnutrition — all drugs for Severe Acute Malnutrition →

Sponsor

Epicentre — full company profile →

Who can join

Adults 6 Weeks to 59 Weeks, any sex, with Severe Acute Malnutrition. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will be conducted as a stratified cluster randomized trial. The unit of randomization will be the outpatient therapeutic feeding center. The 10 health centers will be stratified by size, and centers within a stratum will be randomized in a 1:1 ratio to one of two schedules of treatment: (1) standard weekly visits or (2) monthly visits with support for home-based surveillance.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: A cluster randomized crossover trial.
Hitchings MDT, Berthé F, Aruna P, Shehu I, et al · · 2022 · cited 16× · PMID 35231024 · DOI 10.1371/journal.pmed.1003923
Feasibility of engaging caregivers in at-home surveillance of children with uncomplicated severe acute malnutrition.
Isanaka S, Berthé F, Nackers F, Tang K, et al · · 2020 · cited 12× · PMID 31336045 · DOI 10.1111/mcn.12876
Active and adaptive case finding to estimate therapeutic program coverage for severe acute malnutrition: a capture-recapture study.
Isanaka S, Hedt-Gauthier BL, Salou H, Berthé F, et al · · 2019 · cited 5× · PMID 31842870 · DOI 10.1186/s12913-019-4791-9
Effect of caregiver training on knowledge and confidence of at-home clinical and anthropometric surveillance of children with uncomplicated severe acute malnutrition: analysis of a cross-over cluster randomised trial in Sokoto, Nigeria.
Ali NB, Hitchings MD, Berthé F, Aruna P, et al · · 2025 · PMID 41057203 · DOI 10.1136/bmjgh-2024-018559
Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition: An economic evaluation of a randomized controlled trial.
Menzies NA, Berthé F, Hitchings M, Aruna P, et al · · 2022 · PMID 36962786 · DOI 10.1371/journal.pgph.0001189

Verify or expand the search:

Other recruiting trials for Severe Acute Malnutrition

Currently open trials in the same condition.

NCT06869850 — Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition · NA · recruiting
NCT07089329 — Efficacy of Striatin in Malnourished Children · Phase 3 · recruiting
NCT06010719 — Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition · Phase 4 · recruiting
NCT05994742 — An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM · Phase 3 · active not recruiting
NCT06593080 — The DECIDE-TB Trial; Validation of Treatment Decision Algorithms for Childhood Tuberculosis · NA · recruiting

Other Epicentre trials

Trials by the same sponsor.

NCT06382857 — Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children Wi · NA · recruiting
NCT05551819 — Acceptability of a Microbiome-directed Food in Young Children With Acute Malnutrition · NA · completed
NCT07506213 — Development, Feasibility and Acceptability of Recipes for Locally Available, Specially Formulated Foods for the Manageme · NA · completed
NCT05453253 — Immune Response to a Delayed Second Dose of Oral Cholera Vaccine · Phase 4 · unknown
NCT05449717 — Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03140904 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Epicentre
Last refreshed: 12 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03140904.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing